Identifying weak interdomain interactions that stabilize the supertertiary structure of the N-terminal tandem PDZ domains of PSD-95
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DOI: 10.1038/s41467-018-06133-0
Abstract: Previous studies of the N-terminal PDZ tandem from PSD-95 produced divergent models and failed to identify interdomain contacts stabilizing the structure. We used ensemble and single-molecule FRET along with replica-exchange molecular dynamics to fully characterize… read more here.
Keywords: domains psd; interdomain interactions; pdz domains; interdomain ... See more keywords