Relationship of Seminal Megavesicles, Prostate Median Cysts, and Genotype in Autosomal Dominant Polycystic Kidney Disease
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Magnetic Resonance Imaging"
DOI: 10.1002/jmri.26289
Abstract: Autosomal dominant polycystic kidney disease (ADPKD) can involve prostate and seminal vesicles but the potential interrelationship of these findings and associations with PKD gene mutation locus and type is unknown. read more here.
Keywords: polycystic kidney; autosomal dominant; dominant polycystic; kidney disease ... See more keywords
Colonic diverticular disease in autosomal dominant polycystic kidney disease: is there really an association? A nationwide analysis
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Colorectal Disease"
DOI: 10.1007/s00384-020-03736-2
Abstract: Purpose Colonic diverticulosis, diverticulitis, and diverticular bleeding are reportedly more common in patients with autosomal dominant polycystic kidney disease (ADPKD). Other studies have questioned this association. The objectives of our study are to clarify this… read more here.
Keywords: prevalence; disease; diverticular disease; autosomal dominant ... See more keywords
Insights into autosomal dominant polycystic kidney disease by quantitative mass spectrometry-based proteomics
Sign Up to like & getrecommendations! Published in 2017 at "Cell and Tissue Research"
DOI: 10.1007/s00441-017-2617-9
Abstract: Autosomal dominant polycystic kidney disease (ADPKD) is a common monogenetic disorder that is caused by mutations in the genes PKD1 and PKD2 encoding polycystin-1 and polycystin-2, respectively. Polycystin-1 and -2 form a complex, interact with… read more here.
Keywords: disease; kidney disease; polycystic kidney; autosomal dominant ... See more keywords
Role of apoptosis in the development of autosomal dominant polycystic kidney disease (ADPKD)
Sign Up to like & getrecommendations! Published in 2017 at "Cell and Tissue Research"
DOI: 10.1007/s00441-017-2628-6
Abstract: Autosomal dominant polycystic kidney disease (ADPKD) is a widespread genetic disorder in the Western world and is characterized by cystogenesis that often leads to end-stage renal disease (ESRD). Mutations in the pkd1 gene, encoding for… read more here.
Keywords: apoptosis; disease; autosomal dominant; dominant polycystic ... See more keywords
Relationship between intracranial aneurysms and the severity of autosomal dominant polycystic kidney disease
Sign Up to like & getrecommendations! Published in 2017 at "Acta Neurochirurgica"
DOI: 10.1007/s00701-017-3316-8
Abstract: BackgroundAutosomal dominant polycystic kidney disease (ADPKD) is a hereditary kidney disease characterized by the progressive enlargement of innumerable renal cysts. Although the association of intracranial aneurysms (ICANs) with ADPKD is well known, the relationship between… read more here.
Keywords: kidney; age; disease; polycystic kidney ... See more keywords
Mutation analyses by next-generation sequencing and multiplex ligation-dependent probe amplification in Japanese autosomal dominant polycystic kidney disease patients
Sign Up to like & getrecommendations! Published in 2019 at "Clinical and Experimental Nephrology"
DOI: 10.1007/s10157-019-01736-3
Abstract: BackgroundAutosomal dominant polycystic kidney disease (ADPKD), one of the most common hereditary kidney diseases, causes gradual growth of cysts in the kidneys, leading to renal failure. Owing to the advanced technology of next-generation sequencing (NGS),… read more here.
Keywords: kidney; polycystic kidney; dominant polycystic; next generation ... See more keywords
Natural-derived compounds and their mechanisms in potential autosomal dominant polycystic kidney disease (ADPKD) treatment
Sign Up to like & getrecommendations! Published in 2021 at "Clinical and Experimental Nephrology"
DOI: 10.1007/s10157-021-02111-x
Abstract: Autosomal dominant polycystic kidney disease (ADPKD) is a monogenic kidney disorder that impairs renal functions progressively leading to kidney failure. The disease affects between 1:400 and 1:1000 ratio of the people worldwide. It is caused… read more here.
Keywords: disease; autosomal dominant; dominant polycystic; polycystic kidney ... See more keywords
Repeated aortic dissection in a patient with autosomal dominant polycystic kidney disease
Sign Up to like & getrecommendations! Published in 2022 at "General Thoracic and Cardiovascular Surgery"
DOI: 10.1007/s11748-021-01756-5
Abstract: Autosomal dominant polycystic kidney disease is a systemic disorder associated with cardiovascular complications. However, there are few reports on autosomal dominant polycystic kidney disease-associated aortic dissection. Herein, we present a rare case of a 46-year-old… read more here.
Keywords: autosomal dominant; dominant polycystic; polycystic kidney; aortic dissection ... See more keywords
Total Kidney Volume Is a Prognostic Biomarker of Renal Function Decline and Progression to End-Stage Renal Disease in Patients With Autosomal Dominant Polycystic Kidney Disease
Sign Up to like & getrecommendations! Published in 2017 at "Kidney International Reports"
DOI: 10.1016/j.ekir.2017.01.003
Abstract: Introduction Autosomal dominant polycystic kidney disease is the most common hereditary kidney disease. TKV is a promising imaging biomarker for tracking and predicting the natural history of autosomal dominant polycystic kidney disease. The prognostic value… read more here.
Keywords: kidney; disease; decline; autosomal dominant ... See more keywords
Prognostic Value of Fibroblast Growth Factor 23 in Autosomal Dominant Polycystic Kidney Disease
Sign Up to like & getrecommendations! Published in 2021 at "Kidney International Reports"
DOI: 10.1016/j.ekir.2021.01.004
Abstract: Introduction Autosomal dominant polycystic kidney disease (ADPKD) is characterized by progressive cyst growth and a loss of functioning renal mass, but a decline in glomerular filtration rate (GFR) and onset of end-stage renal disease (ESRD)… read more here.
Keywords: disease; autosomal dominant; dominant polycystic; polycystic kidney ... See more keywords
Long Residence Time at the Vasopressin V2 Receptor Translates into Superior Inhibitory Effects in Ex Vivo and In Vivo Models of Autosomal Dominant Polycystic Kidney Disease.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of medicinal chemistry"
DOI: 10.1021/acs.jmedchem.2c00011
Abstract: Prevailing strategies directing early-phase drug discovery heavily rely on equilibrium-based metrics such as affinity, which overlooks the kinetic process of a drug molecule interacting with its target. Herein, we developed a number of vasopressin V2… read more here.
Keywords: polycystic kidney; vasopressin receptor; residence time; autosomal dominant ... See more keywords