A dominant RAD51C pathogenic splicing variant predisposes to breast and ovarian cancer in the Newfoundland population due to founder effect
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DOI: 10.1002/mgg3.1070
Abstract: RAD51C is important in DNA repair and individuals with pathogenic RAD51C variants have increased risk of hereditary breast and ovarian cancer syndrome (HBOC), an autosomal dominant genetic predisposition to early onset breast and/or ovarian cancer. read more here.
Keywords: rad51c pathogenic; breast ovarian; ovarian cancer; dominant rad51c ... See more keywords