A dominant tubulin mutation causes cerebellar neurodegeneration in a genetic model of tubulinopathy
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DOI: 10.1126/sciadv.abf7262
Abstract: Mutations in tubulins cause distinct neurodevelopmental and degenerative diseases termed “tubulinopathies”; however, little is known about the functional requirements of tubulins or how mutations cause cell-specific pathologies. Here, we identify a mutation in the gene… read more here.
Keywords: cell; mutation causes; dominant tubulin; mutation ... See more keywords