Prognostic histologic subtyping of dominant tumor in resected synchronous multiple adenocarcinomas of lung
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DOI: 10.1038/s41598-021-88193-9
Abstract: The prognostic role of histological patterns of dominant tumor (DT) and second dominant tumor (sDT) in synchronous multiple adenocarcinoma (SMADC) of lung remains unclear. SMADC patients diagnosed between 2003 and 2015 were retrospectively reviewed. DT… read more here.
Keywords: synchronous multiple; dominant tumor; sdt; high grade ... See more keywords
Treg-Dominant Tumor Microenvironment Is Responsible for Hyperprogressive Disease after PD-1 Blockade Therapy
Sign Up to like & getrecommendations! Published in 2022 at "Cancer Immunology Research"
DOI: 10.1158/2326-6066.cir-22-0041
Abstract: The mechanisms underlying hyperprogressive disease (HPD) associated with PD-1 blockade are unclear. The authors develop a way to reproduce HPD by partially eliminating CD8+ T cells with NIR-PIT, creating a regulatory T cell–dominant tumor microenvironment… read more here.
Keywords: dominant tumor; tumor microenvironment; tumor; hyperprogressive disease ... See more keywords