Dominating the Negative: How DNMT3A Mutations Contribute to AML Pathogenesis.
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DOI: 10.1016/j.stem.2016.12.008
Abstract: Somatic mutations in DNMT3A are one of the most prevalent genetic abnormalities found in acute myeloid leukemia (AML) patients. A new study by Guryanova et al. sheds mechanistic insight into how the most common DNMT3A variant… read more here.
Keywords: dnmt3a mutations; dominating negative; dnmt3a; negative dnmt3a ... See more keywords