Palladium-Catalyzed Domino Alkenylation/Amination/Pyridination Reactions of 2-Vinylanilines with Alkynes: Access to Cyclopentaquinolines.
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DOI: 10.1021/acs.orglett.7b03164
Abstract: A novel domino oxidative annulation of 2-vinylanilines with internal alkynes was developed to constitute a rare class of cyclopentaquinoline derivatives. This transformation encompasses four σ bonds formation, one quaternary carbon center construction, and pyridination steps… read more here.
Keywords: domino; pyridination; palladium catalyzed; alkenylation amination ... See more keywords