Construction of benzo[d]imidazo[2,1-b]thiazole derivatives via a simple multi-component domino cyclization
Sign Up to like & getrecommendations! Published in 2017 at "Research on Chemical Intermediates"
DOI: 10.1007/s11164-017-3123-0
Abstract: An operationally simple and highly efficient one-pot multi-component domino cyclization for the preparation of benzo[d]imidazo[2,1-b]thiazole derivatives from 2-amine-benzo[d]thiazoles, 2-oxoaldehyde and cyclic 1,3-dicarbonyl compounds under microwave irradiation has been developed in this work. Formation of the… read more here.
Keywords: imidazo thiazole; domino cyclization; component domino; multi component ... See more keywords
Mechanism and origins of gold-catalyzed domino cyclization to spiroindolines: the role of periplanar cooperation and hydrogen bonding interactions
Sign Up to like & getrecommendations! Published in 2020 at "Organic chemistry frontiers"
DOI: 10.1039/d0qo00359j
Abstract: The detailed mechanism and origins of gold-catalyzed domino cyclization to indoloazocines by density functional theory are systematically studied. The energy profiles for [Au(PMe3)]+ and [Au(PMe3)SbF6] were investigated. Specifically, the gold-counterion dual catalysis mechanism was the… read more here.
Keywords: hydrogen bonding; domino cyclization; mechanism; bonding interactions ... See more keywords
Copper-catalyzed aerobic oxidative domino cyclization of methyl azaarenes with 6-amino-pyrimidine-2,4-diones and pyrazol-5-amines: access to dipyrimidine/dipyrazolo-fused pyridines
Sign Up to like & getrecommendations! Published in 2021 at "Organic chemistry frontiers"
DOI: 10.1039/d0qo01588a
Abstract: An aerobic copper-catalyzed oxidative domino cyclization of methyl azaarenes with 6-amino-pyrimidine-2,4-diones and pyrazol-5-amines has been developed, which enables access to dipyrimidine/dipyrazolo-fused pyridines. Cu(OTf)2 is used as a transition-metal catalyst. The oxidative annulation procedure exhibits excellent… read more here.
Keywords: methyl; cyclization methyl; oxidative domino; domino cyclization ... See more keywords
Photoredox/copper cocatalyzed domino cyclization of oxime esters with TMSCN: access to antifungal active tetrasubstituted pyrazines.
Sign Up to like & getrecommendations! Published in 2022 at "Chemical communications"
DOI: 10.1039/d2cc02480b
Abstract: A photoredox/copper cocatalyzed domino cyclization of oxime esters with TMSCN has been developed. A range of structurally novel tetrasubstituted pyrazines have been obtained. This method features high bond-forming efficiency, high step economy, broad substrate scope,… read more here.
Keywords: oxime esters; domino cyclization; cocatalyzed domino; copper cocatalyzed ... See more keywords
Copper-Catalyzed Photoinduced Radical Domino Cyclization of Ynamides and Cyanamides: a Unified Entry to Rosettacin, Luotonin A and Deoxyvasicinone
Sign Up to like & getrecommendations! Published in 2018 at "Synthesis"
DOI: 10.1055/s-0037-1610134
Abstract: A general and efficient procedure for the copper-catalyzed photoinduced radical domino cyclization of ynamides and cyanamides providing an efficient access to complex tri-, tetra- and pentacyclic nitrogen heterocycles is reported. Upon visible light irradiation in… read more here.
Keywords: catalyzed photoinduced; domino cyclization; copper catalyzed; radical domino ... See more keywords