Domino Reaction Encoded Heterogeneous Colloidal Microswarm with On-Demand Morphological Adaptability.
Sign Up to like & getrecommendations! Published in 2021 at "Advanced materials"
DOI: 10.1002/adma.202100070
Abstract: Emulating natural swarm intelligence with group-level functionality in artificial micro/nanorobotic systems offers an opportunity to sublimate the limited functions of individuals and revolutionize their applications. However, achieving synchronous operation of microswarms with environmental adaptability and… read more here.
Keywords: reaction encoded; domino reaction; adaptability; microswarm ... See more keywords
Synthesis of polysubstituted phenyl acetates via FeCl3-mediated domino reaction of 2-(aryl(piperidin-1-yl)methyl)phenols and 1,3-diketones
Sign Up to like & getrecommendations! Published in 2017 at "Tetrahedron"
DOI: 10.1016/j.tet.2017.10.045
Abstract: Abstract A one-pot domino reaction involving Lewis acid-mediated nucleophilic-substitution/intramolecular-cyclization/reverse Claisen condensation of 2-(aryl(piperidin-1-yl)methyl)phenols and 1,3-diketones has been developed for the synthesis of 2-(3-oxo-1-phenylbutyl)phenyl acetates in good to excellent yields (77%–95%). The construction of the products… read more here.
Keywords: methyl phenols; domino reaction; domino; aryl piperidin ... See more keywords
Lewis Acid-Catalyzed Diastereoselective Domino Reaction of Ene-Ynamide with Trimethylsilyl Cyanide to Construct Spiroindolines.
Sign Up to like & getrecommendations! Published in 2022 at "Organic letters"
DOI: 10.1021/acs.orglett.2c01607
Abstract: The Zn(OTf)2-catalyzed domino reaction of enamide-ynamides in the presence of trimethylsilyl cyanide as an external nucleophile to construct spirocyclic indolines was developed. This domino reaction involved cyclization of enamide to ynamide to generate 4',5'-dihydrospiro[indoline-3,3'-pyrrol]-1'-ium followed… read more here.
Keywords: reaction; trimethylsilyl cyanide; domino reaction; lewis acid ... See more keywords
I2/FeCl3-Catalyzed Domino Reaction of Aurones with Enamino Esters for the Synthesis of Highly Functionalized Pyrroles.
Sign Up to like & getrecommendations! Published in 2022 at "Organic letters"
DOI: 10.1021/acs.orglett.2c03537
Abstract: A novel and efficient I2/FeCl3-catalyzed domino reaction of aurones with enamino esters via Michael addition, iodination, intramolecular nucleophilic substitution, and spiro ring opening processes has been developed, affording a vast variety of polysubstituted pyrroles in… read more here.
Keywords: reaction; fecl3 catalyzed; domino reaction; aurones enamino ... See more keywords
Silver-Catalyzed Domino Reaction of CF3-Substituted N-Allenamides with Primary Amines for the Construction of 2-Amido-5-fluoropyrroles.
Sign Up to like & getrecommendations! Published in 2023 at "Organic letters"
DOI: 10.1021/acs.orglett.3c00401
Abstract: We report herein a domino reaction to construct 2-amido-5-fluoropyrroles from CF3-substituted N-allenamides. The in situ generated gem-difluorinated ene-ynamides derived from CF3-substituted N-allenamides, when subjected to silver catalysis with a primary amine, undergo simultaneous hydroamination of… read more here.
Keywords: construction amido; cf3 substituted; substituted allenamides; domino reaction ... See more keywords
Asymmetric Synthesis of Functionalized Tricyclic Chromanes via an Organocatalytic Triple Domino Reaction.
Sign Up to like & getrecommendations! Published in 2017 at "Organic letters"
DOI: 10.1021/acs.orglett.7b01322
Abstract: A highly stereoselective triple domino reaction for the synthesis of functionalized tricyclic chromane scaffolds has been developed. A secondary amine-catalyzed domino Michael/Michael/aldol condensation reaction between aliphatic aldehydes, nitro-chromenes, and α,β-unsaturated aldehydes leads to the formation… read more here.
Keywords: domino reaction; synthesis functionalized; domino; reaction ... See more keywords
Palladium-Catalyzed 4-Fold Domino Reaction for the Synthesis of a Polymeric Double Switch.
Sign Up to like & getrecommendations! Published in 2018 at "Organic letters"
DOI: 10.1021/acs.orglett.8b00553
Abstract: A palladium-catalyzed 4-fold domino reaction consisting of two carbopalladation reactions and two C-H activation reactions, followed by the introduction of an acrylate moiety, led to the tetra-substituted helical alkene A2, using the dialkyne A3 as… read more here.
Keywords: palladium catalyzed; catalyzed fold; fold domino; domino reaction ... See more keywords
ZnCl2-promoted domino reaction of 2-hydroxybenzonitriles with ketones for synthesis of 1,3-benzoxazin-4-ones
Sign Up to like & getrecommendations! Published in 2021 at "RSC Advances"
DOI: 10.1039/d1ra04194k
Abstract: A method for the synthesis of 1,3-benzoxazine-4-ketone was developed using 2-hydroxybenzonitriles and ketones as raw materials with the promotion of ZnCl2. read more here.
Keywords: domino reaction; promoted domino; hydroxybenzonitriles ketones; zncl2 promoted ... See more keywords
A New Domino Reaction under Microwave Irradiation for the Synthesis of Pyrazolo[5,1- b ]quinazolinones
Sign Up to like & getrecommendations! Published in 2023 at "Synthesis"
DOI: 10.1055/a-2075-3140
Abstract: Pyrazolo[5,1-b]quinazolinones were synthesized by consecutive pyrazole and quinazolinone ring closures in a new catalyst-free microwave-promoted domino reaction of hydrazine with 2-cyano-3-(methylthio)-3-(2-methoxycarbonylphenylamino)acrylates, which were prepared from methyl anthranilate and 2-cyano-3,3-bis(methylthio)acrylates. When 2-cyano-3,3-bis(methylthio)acrylates reacted directly with anthranilic… read more here.
Keywords: pyrazolo quinazolinones; domino reaction; synthesis;
One-pot four-component domino reaction for the synthesis of bifunctionalized spiro[indazolo[3,2-b]quinazoline-7,3′-indoline hybrids: A green approach
Sign Up to like & getrecommendations! Published in 2019 at "Synthetic Communications"
DOI: 10.1080/00397911.2019.1566475
Abstract: Abstract An efficient tandem route to obtain novel spiro[indazolo[3,2-b]quinazoline-7,3′-indolines has been explored. The one-step domino reaction proceeds via in situ generation of the 1H-indazol-3-amines followed by its reaction with the cyclic 1,3-dicarbonyls and isatin derivatives… read more here.
Keywords: spiro indazolo; indazolo quinazoline; domino reaction;
Gold(I)-Catalyzed Domino Reaction for Furopyrans Synthesis
Sign Up to like & getrecommendations! Published in 2020 at "Molecules"
DOI: 10.3390/molecules25214976
Abstract: We report herein an efficient synthesis of furopyran derivatives through a gold(I)-catalyzed domino reaction. The cascade reaction starts with two regioselective cyclizations, a 5-endo-dig and a 8-endo-dig, followed with a Grob-type fragmentation and a hetero… read more here.
Keywords: domino reaction; reaction; catalyzed domino; reaction furopyrans ... See more keywords