Fast analysis of domoic acid using microchip electrophoresis with laser-induced fluorescence detection.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of separation science"
DOI: 10.1002/jssc.201600982
Abstract: A fast and effective method was developed to detect domoic acid based upon microchip electrophoresis combined with laser-induced fluorescence detection. Through study of the gated injection process on the cross channel of the microchip, the… read more here.
Keywords: detection; microchip electrophoresis; induced fluorescence; domoic acid ... See more keywords
Potential endocrine correlation with exposure to domoic acid in Southern Right Whale (Eubalaena australis) at the Península Valdés breeding ground.
Sign Up to like & getrecommendations! Published in 2021 at "Oecologia"
DOI: 10.1007/s00442-021-05078-4
Abstract: In waters off Península Valdés (PV), Argentina, southern right whales (SRW, Eubalaena australis) are occasionally exposed to domoic acid (DA), a neurotoxin produced by diatoms of the genus Pseudo-nitzschia. Domoic acid toxicity in marine mammals… read more here.
Keywords: southern right; nsula vald; exposure; domoic acid ... See more keywords
Domoic acid suppresses hyperexcitation in the network due to activation of kainate receptors of GABAergic neurons.
Sign Up to like & getrecommendations! Published in 2019 at "Archives of biochemistry and biophysics"
DOI: 10.1016/j.abb.2019.06.004
Abstract: Kainate receptors play an important role in the brain. They contribute to postsynaptic depolarization, modulate the release of neurotransmitters such as GABA and glutamate, affect the development of the neuronal network. At the same time,… read more here.
Keywords: network; domoic acid; kainate receptors; activation ... See more keywords
Domoic acid in California sea lion fetal fluids indicates continuous exposure to a neuroteratogen poses risks to mammals.
Sign Up to like & getrecommendations! Published in 2018 at "Harmful algae"
DOI: 10.1016/j.hal.2018.06.003
Abstract: Domoic acid (DA) is a neuroexcitotoxic amino acid that is naturally produced by some species of marine diatoms during harmful algal blooms (HABs). The toxin is transferred through the food web from plantivorous fish and… read more here.
Keywords: continuous exposure; exposure; domoic acid; california sea ... See more keywords
The successional formation and release of domoic acid in a Pseudo-nitzschia bloom in the Juan de Fuca Eddy: A drifter study.
Sign Up to like & getrecommendations! Published in 2018 at "Harmful algae"
DOI: 10.1016/j.hal.2018.08.007
Abstract: Blooms of Pseudo-nitzschia species are frequent, but presently unpredictable, in the Juan de Fuca Eddy region off the coasts of Washington (US) and British Columbia (Canada). This upwelling eddy region is proposed to be the… read more here.
Keywords: bloom; study; domoic acid; pseudo nitzschia ... See more keywords
Effects of ocean acidification on the growth, photosynthetic performance, and domoic acid production of the diatom Pseudo-nitzschia australis from the California Current System.
Sign Up to like & getrecommendations! Published in 2021 at "Harmful algae"
DOI: 10.1016/j.hal.2021.102030
Abstract: Pseudo-nitzschia australis (Frenguelli), a toxigenic pennate diatom capable of producing the neurotoxin domoic acid (DA), was examined in unialgal laboratory cultures to quantify its physiological response to ocean acidification (OA) - the decline in pH… read more here.
Keywords: production; nitzschia australis; ocean acidification; domoic acid ... See more keywords
Neurobehavioral assessment of mice following repeated oral exposures to domoic acid during prenatal development.
Sign Up to like & getrecommendations! Published in 2017 at "Neurotoxicology and teratology"
DOI: 10.1016/j.ntt.2017.09.002
Abstract: Domoic acid (DA) is an algal toxin which has been associated with significant neurotoxicity in humans, non-human primates, rodents, and marine mammals. Developmental exposure to DA is believed to result in neurotoxicity that may persist… read more here.
Keywords: oral exposures; assessment mice; domoic acid; neurobehavioral assessment ... See more keywords
Effects of oral domoic acid exposure on maternal reproduction and infant birth characteristics in a preclinical nonhuman primate model.
Sign Up to like & getrecommendations! Published in 2019 at "Neurotoxicology and teratology"
DOI: 10.1016/j.ntt.2019.01.001
Abstract: Domoic Acid (DA) is a naturally-occurring excitotoxin, produced by marine algae, which can bioaccumulate in shellfish and finfish. The consumption of seafood contaminated with DA is associated with gastrointestinal illness that, in the case of… read more here.
Keywords: primate model; birth; exposure; domoic acid ... See more keywords
Effect of the antioxidant N-acetylcysteine on the depuration of the amnesic shellfish poisoning toxin, domoic acid, in the digestive gland of the king scallop Pecten maximus
Sign Up to like & getrecommendations! Published in 2023 at "Aquatic Living Resources"
DOI: 10.1051/alr/2023011
Abstract: Domoic acid (DA) is a potent neurotoxin produced by worldwide distributed diatoms of the genus Pseudo-nitzchia (PSN) and is responsible for Amnesic Shellfish Poisoning (ASP) in humans. King scallop Pecten maximus, a bivalve species of… read more here.
Keywords: scallop pecten; depuration; king scallop; amnesic shellfish ... See more keywords
Toxicokinetics and Physiologically Based Pharmacokinetic Modeling of the Shellfish Toxin Domoic Acid in Nonhuman Primates
Sign Up to like & getrecommendations! Published in 2018 at "Drug Metabolism and Disposition"
DOI: 10.1124/dmd.117.078485
Abstract: Domoic acid (DA), a neurotoxin, is produced by marine algae and has caused toxications worldwide in animals and humans. However, the toxicokinetics of DA have not been fully evaluated, and information is missing on the… read more here.
Keywords: disposition; based pharmacokinetic; domoic acid; physiologically based ... See more keywords
Transcriptomic responses to grazing reveal the metabolic pathway leading to the biosynthesis of domoic acid and highlight different defense strategies in diatoms
Sign Up to like & getrecommendations! Published in 2019 at "BMC Molecular Biology"
DOI: 10.1186/s12867-019-0124-0
Abstract: BackgroundA major cause of phytoplankton mortality is predation by zooplankton. Strategies to avoid grazers have probably played a major role in the evolution of phytoplankton and impacted bloom dynamics and trophic energy transport. Certain species… read more here.
Keywords: biosynthesis; defense; defense strategies; domoic acid ... See more keywords