Modification and characterization of an innovative polyvinyl alcohol-45S5 bioactive glass nanocomposite scaffold containing Donepezil hydrochloride for bone tissue engineering applications
Sign Up to like & getrecommendations! Published in 2021 at "Materials Letters"
DOI: 10.1016/j.matlet.2021.130160
Abstract: Abstract The bone tissue engineering field is in desperate need of a suitable scaffold. We synthesized a polyvinyl alcohol (PVA) based scaffold and modified it by adding bioglass (BG) and Donepezil hydrochloride (DPH) to offset… read more here.
Keywords: tissue engineering; polyvinyl alcohol; donepezil hydrochloride; bone tissue ... See more keywords
Development of HPLC method coupled with fluorescence detection for simultaneous determination of donepezil HCl and trazodone HCl in spiked human plasma and tablets dosage forms.
Sign Up to like & getrecommendations! Published in 2019 at "Annales pharmaceutiques francaises"
DOI: 10.1016/j.pharma.2019.02.003
Abstract: OBJECTIVES Elderly people with dementia are commonly suffered from sleep disorders. So, the use of Donepezil hydrochloride as anti-Alzheimer drug and Trazodone hydrochloride as antidepressants with hypnotic action is very important in these cases. This… read more here.
Keywords: donepezil hydrochloride; hydrochloride; trazodone hydrochloride; human plasma ... See more keywords
A sustainable UPLC-UV method for quantification of donepezil hydrochloride in biorelevant media applied to dissolution profile comparison
Sign Up to like & getrecommendations! Published in 2020 at "Drug Development and Industrial Pharmacy"
DOI: 10.1080/03639045.2020.1810266
Abstract: Abstract Donepezil hydrochloride is one of the most prescribed anti-Alzheimer’s drugs, despite being available for more than two decades, chromatographic methods for the quantification of the drug in biorelevant media that mimics pH physiological conditions… read more here.
Keywords: donepezil hydrochloride; biorelevant media; sustainable uplc; method ... See more keywords
Recent developments in the design and synthesis of benzylpyridinium salts: Mimicking donepezil hydrochloride in the treatment of Alzheimer’s disease
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Chemistry"
DOI: 10.3389/fchem.2022.936240
Abstract: Background: Alzheimer’s disease (AD) is an advanced and irreversible degenerative disease of the brain, recognized as the key reason for dementia among elderly people. The disease is related to the reduced level of acetylcholine (ACh)… read more here.
Keywords: donepezil hydrochloride; benzylpyridinium salts; disease; alzheimer disease ... See more keywords