During acute graft versus host disease CD28 deletion in donor CD8+, but not CD4+, T cells maintain antileukemia responses in mice
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DOI: 10.1002/eji.201847669
Abstract: Donor lymphocyte infusions together with allogeneic hematopoietic stem cell transplantation are routinely used as second‐line treatment for hematological malignancies. Mature T cells in the graft crucially mediate a graft versus leukemia (GvL) response, but also… read more here.
Keywords: donor; donor cd8; cd4; graft versus ... See more keywords