Early achievement of full donor chimerism after allogeneic hematopoietic stem cell transplantation predicts lower relapse risk in patients with acute lymphoblastic leukemia
Sign Up to like & getrecommendations! Published in 2018 at "Journal of the Chinese Medical Association"
DOI: 10.1016/j.jcma.2018.06.005
Abstract: Background: Acute lymphoblastic leukemia (ALL) remains one of the most difficult‐to‐cure hematological malignancies. Allogeneic hematopoietic stem cell transplantation (HSCT) provides curative potential but a substantial proportion of patients eventually will relapse. It is unknown if… read more here.
Keywords: chimerism; donor chimerism; relapse; acute lymphoblastic ... See more keywords
Systematic comparison of donor chimerism in peripheral blood and bone marrow after hematopoietic stem cell transplantation
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DOI: 10.1038/bcj.2017.42
Abstract: Incomplete donor chimerism (DC) after hematopoietic stem cell transplantation (HSCT) is associated with reduced overall and disease-free survival and decreasing DC can precede overt relapse of malignant diseases.1, 2 Sensitive chimerism quantification may therefore allow… read more here.
Keywords: chimerism; donor chimerism; cell transplantation; stem cell ... See more keywords
Donor chimerism and immune reconstitution following haploidentical transplantation in sickle cell disease
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.1055497
Abstract: Introduction We previously reported the initial results of a phase II multicenter transplant trial using haploidentical parental donors for children and aolescents with high-risk sickle cell disease achieving excellent survival with exceptionally low rates of… read more here.
Keywords: immune reconstitution; cell; donor chimerism; disease ... See more keywords