Deceased-Donor Kidneys: Is Past Performance an Indicator of Future Transplant Success?
Sign Up to like & getrecommendations! Published in 2021 at "Kidney International Reports"
DOI: 10.1016/j.ekir.2021.06.009
Abstract: T here continues to be a disparity between the number of kidneys available for transplantation and the number of patients with end-stage kidney disease. Although kidney transplantation remains the best treatment option for most patients… read more here.
Keywords: donor kidneys; past performance; indicator future; performance indicator ... See more keywords
Quality Assessment of Donor Kidneys and the Tendency of Kidney Acceptance: A Single-Center Experience.
Sign Up to like & getrecommendations! Published in 2021 at "Transplantation proceedings"
DOI: 10.1016/j.transproceed.2021.01.041
Abstract: PURPOSE The increasing age of donors and the increasing tendency of comorbidities requires an extension in acceptance criteria. In this review, the tendency for acceptance and refusal was analyzed by examining reasons for declining donor… read more here.
Keywords: donor kidneys; tendency; donor; center ... See more keywords
Overcoming Mismatch Concerns for Adult Recipients of Small Pediatric Deceased Donor Kidneys.
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DOI: 10.1016/j.transproceed.2021.03.030
Abstract: BACKGROUND Kidneys from very young pediatric donors continue to be underutilized. To reduce discard, the Organ Procurement and Transplantation Network (OPTN) policy was recently updated to allow kidneys from donors weighing read more here.
Keywords: donor kidneys; bloc; adult recipients; overcoming mismatch ... See more keywords
Evaluating non-utilization of deceased donor kidneys in Korea
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DOI: 10.1038/s41598-025-86998-6
Abstract: Considering the low deceased donation rates despite increasing rates of end-stage kidney disease in Asia, minimizing donor kidney discard is important. This study aimed to investigate the current situation of donor kidney discard in Korea.… read more here.
Keywords: donor kidneys; non utilization; kidney discard; deceased donor ... See more keywords
Safety and feasibility of 2 h of normothermic machine perfusion of donor kidneys in the Eurotransplant Senior Program
Sign Up to like & getrecommendations! Published in 2021 at "BJS Open"
DOI: 10.1093/bjsopen/zraa024
Abstract: Abstract Background The 5-year graft survival rate of donor kidneys transplanted in the Eurotransplant Senior Program (ESP) is only 47 per cent. Normothermic machine perfusion (NMP) may be a new preservation technique that improves graft… read more here.
Keywords: donor kidneys; machine perfusion; outcome; safety feasibility ... See more keywords
How small is too small and how young is too young when allocating pediatric deceased donor kidneys to optimize kidney transplant rates?
Sign Up to like & getrecommendations! Published in 2019 at "Transplantation"
DOI: 10.1097/tp.0000000000002705
Abstract: I this issue of the journal, Suneja et al present a very informative analysis of the usage of small (donor age read more here.
Keywords: donor kidneys; small young; small small; deceased donor ... See more keywords
Tissue-resident Lymphocytes Are Released During Hypothermic and Normothermic Machine Perfusion of Human Donor Kidneys
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DOI: 10.1097/tp.0000000000004936
Abstract: Background. Machine perfusion is the preferred preservation method for deceased donor kidneys. Perfusate fluid, which contains a complex mixture of components, offers potential insight into the organ’s viability and function. This study explored immune cell… read more here.
Keywords: donor kidneys; perfusion; tissue resident; machine perfusion ... See more keywords
Targeting Kidney Inflammation After Brain Death and Cold Storage: Investigating the Potential of an NLRP3 Inflammasome Inhibitor (MCC950) for Preconditioning Donor Kidneys
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DOI: 10.1097/tp.0000000000005211
Abstract: Background. Brain death (BD) and cold storage (CS) are critical factors that induce inflammation in donor kidneys, compromising organ quality. We investigated whether treating kidneys from BD rats with an inflammasome Nod-like receptor family pyrin… read more here.
Keywords: donor kidneys; brain death; inflammation; cold storage ... See more keywords
Impact of Cold Ischemia Time on Outcomes of Deceased Donor Kidney Transplantation: An Analysis of a National Registry
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DOI: 10.1097/txd.0000000000000888
Abstract: Background. Cold ischemia time (CIT) is known to impact kidney graft survival rates. We compare the impact of CIT on graft failure and mortality in circulatory death versus brain death donor kidneys and how it… read more here.
Keywords: donor kidneys; cold ischemia; circulatory death; death ... See more keywords
MicroRNA antagonist therapy during normothermic machine perfusion of donor kidneys
Sign Up to like & getrecommendations! Published in 2021 at "American Journal of Transplantation"
DOI: 10.1111/ajt.16929
Abstract: Normothermic machine perfusion (NMP) is a novel clinical approach to overcome the limitations of traditional hypothermic organ preservation. NMP can be used to assess and recondition organs prior to transplant and is the subject of… read more here.
Keywords: donor kidneys; therapy; perfusion; machine perfusion ... See more keywords
(Pro)renin, Erythropoietin, Vitamin D and Urodilatin Release From Human Donor Kidneys During Normothermic Machine Perfusion: Predictors of Early Post‐Transplant Outcome?
Sign Up to like & getrecommendations! Published in 2025 at "Clinical Transplantation"
DOI: 10.1111/ctr.70163
Abstract: Human donor kidneys release (pro)renin, erythropoietin (EPO), active vitamin D, and urodilatin during normothermic machine perfusion (NMP). However, whether the endocrine function of donor kidneys is associated with post‐transplant kidney function is unclear. read more here.
Keywords: renin erythropoietin; pro renin; vitamin urodilatin; donor kidneys ... See more keywords