Gene expression differences between matched pairs of ovarian cancer patient tumors and patient-derived xenografts
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DOI: 10.1038/s41598-019-42680-2
Abstract: As patient derived xenograft (PDX) models are increasingly used for preclinical drug development, strategies to account for the nonhuman component of PDX RNA expression data are critical to its interpretation. A bioinformatics pipeline to separate… read more here.
Keywords: pdx donor; donor tumors; expression; pdx ... See more keywords