Homology modelling, molecular docking, and molecular dynamics simulations reveal the inhibition of Leishmania donovani dihydrofolate reductase-thymidylate synthase enzyme by Withaferin-A
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DOI: 10.1186/s13104-018-3354-1
Abstract: ObjectivePresent in silico study was carried out to explore the mode of inhibition of Leishmania donovani dihydrofolate reductase-thymidylate synthase (Ld DHFR-TS) enzyme by Withaferin-A, a withanolide isolated from Withania somnifera. Withaferin-A (WA) is known for… read more here.
Keywords: inhibition leishmania; dhfr; donovani dihydrofolate; enzyme ... See more keywords