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Published in 2020 at "Cytokine"
DOI: 10.1016/j.cyto.2020.155319
Abstract: Leishmania donovani, a protozoan parasite, inflicts the disease Visceral leishmaniasis (VL) Worldwide. The only orally bioavailable drug miltefosine is toxic, whereas liposomal amphotericin B (AmpB) is expensive. Lupeol, a triterpenoid from Sterculia villosa bark, was…
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Keywords:
leishmanial immunomodulatory;
anti leishmanial;
lupeol;
immunomodulatory effects ... See more keywords
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Published in 2022 at "Parasitology"
DOI: 10.1017/s0031182022000610
Abstract: Abstract Abstract The gold standard for diagnosis of leishmaniasis is the microscopic detection of amastigotes/Leishman Donovan (LD) bodies, but its moderate sensitivity necessitates the development of molecular approaches. This study aimed to quantify in experimental…
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Keywords:
donovani infected;
monitoring;
amastigote specific;
leishmaniasis ... See more keywords
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Published in 2022 at "Microbiology Spectrum"
DOI: 10.1128/spectrum.02699-22
Abstract: People who reside in regions where leishmaniasis is endemic and who lack proteins, iron, zinc, and vitamin A in their diet are more prone to develop visceral leishmaniasis (VL) as a full-blown disease. Vitamin A…
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Keywords:
donovani infected;
leishmania donovani;
cholesterol;
mtor ... See more keywords
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Published in 2019 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2019.02360
Abstract: Altered sialylation is generally maintained by a fine balance between sialidases and sialyltransferases, which plays an essential role during disease pathogenesis. TLR4 is a membrane-bound highly sialylated glycoprotein predominantly having α2,3-linked sialic acids. It is…
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Keywords:
modulation tlr4;
infected macrophages;
sialylation;
donovani infected ... See more keywords