Influence of chronic L-DOPA treatment on immune response following allogeneic and xenogeneic graft in a rat model of Parkinson’s disease
Sign Up to like & getrecommendations! Published in 2017 at "Brain, Behavior, and Immunity"
DOI: 10.1016/j.bbi.2016.11.014
Abstract: Highlights • Evaluation of clinical parameters that could influence the success of cell therapy.• L-DOPA does not impair rodent graft viability.• L-DOPA treatment following transplantation can influence the host immune response.• Cell transplant prior to… read more here.
Keywords: graft; dopa treatment; dopa; immune response ... See more keywords
Striatonigral neurons divide into two distinct morphological-physiological phenotypes after chronic L-DOPA treatment in parkinsonian rats
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-28273-5
Abstract: Dendritic regression of striatal spiny projection neurons (SPNs) is a pathological hallmark of Parkinson’s disease (PD). Here we investigate how chronic dopamine denervation and dopamine replacement with L-DOPA affect the morphology and physiology of direct… read more here.
Keywords: chronic dopa; dopa treatment; dopa; physiology ... See more keywords