Association of Stimulant Use With Dopaminergic Alterations in Users of Cocaine, Amphetamine, or Methamphetamine: A Systematic Review and Meta-analysis
Sign Up to like & getrecommendations! Published in 2017 at "JAMA Psychiatry"
DOI: 10.1001/jamapsychiatry.2017.0135
Abstract: Importance Stimulant use disorder is common, affecting between 0.3% and 1.1% of the population, and costs more than $85 billion per year globally. There are no licensed treatments to date. Several lines of evidence implicate… read more here.
Keywords: availability; amphetamine methamphetamine; dopamine; stimulant users ... See more keywords
On‐Demand Chemomagnetic Modulation of Striatal Neurons Facilitated by Hybrid Magnetic Nanoparticles
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Functional Materials"
DOI: 10.1002/adfm.202204732
Abstract: Minimally invasive manipulation of cell signaling is critical in basic neuroscience research and in developing therapies for neurological disorders. Here, a wireless chemomagnetic neuromodulation platform for the on‐demand control of primary striatal neurons that relies… read more here.
Keywords: hybrid magnetic; dopamine; poegma; magnetic nanoparticles ... See more keywords
Motor progression and nigrostriatal neurodegeneration in Parkinson's disease.
Sign Up to like & getrecommendations! Published in 2022 at "Annals of neurology"
DOI: 10.1002/ana.26373
Abstract: OBJECTIVE The motor severity in Parkinson's disease (PD) is believed to parallel with dopaminergic terminal degeneration in the striatum although the terminal was reported to be virtually absent by 4 years post-diagnosis. Meanwhile, neuromelanin-laden dopamine neuron… read more here.
Keywords: dopamine; dopamine neuron; parkinson disease; loss ... See more keywords
Dopaminergic signaling regulates zebrafish larvae's response to electricity
Sign Up to like & getrecommendations! Published in 2022 at "Biotechnology Journal"
DOI: 10.1002/biot.202100561
Abstract: Electrical stimulation of brain or muscle activities has gained attention for studying the molecular and cellular mechanisms involved in electric‐induced responses. We recently showed zebrafish's response to electricity. Here, we hypothesized that this response is… read more here.
Keywords: response electricity; response; zebrafish larvae; dopamine ... See more keywords
Mimicking Natural Metabolisms: Cell‐Free Flow Preparation of Dopamine
Sign Up to like & getrecommendations! Published in 2022 at "ChemBioChem"
DOI: 10.1002/cbic.202200462
Abstract: The biosynthesis of dopamine (DA) from L‐tyrosine as starting material is an excellent yet challenging strategy. Here we developed a versatile, multi‐enzymatic platform for the biocatalytic preparation of DA in a continuous mode with excellent… read more here.
Keywords: mimicking natural; natural metabolisms; cell free; preparation ... See more keywords
Sonic hedgehog expression in zebrafish forebrain identifies the teleostean pallidal signaling center and shows preglomerular complex and posterior tubercular dopamine cells to arise from shh cells
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Comparative Neurology"
DOI: 10.1002/cne.24825
Abstract: Ventralization, a major patterning process in the developing vertebrate neural tube (central nervous system, CNS), depends on Sonic hedgehog (SHH) as a main signaling morphogen. We studied the CNS of late larval and young adult… read more here.
Keywords: shh gfp; dopamine; shh; sonic hedgehog ... See more keywords
Adolescent chronic unpredictable stress causes a bias in goal-directed behavior and distinctively changes the expression of NMDA and dopamine receptors in the dorsomedial and dorsolateral striatum in male rats.
Sign Up to like & getrecommendations! Published in 2022 at "Developmental psychobiology"
DOI: 10.1002/dev.22235
Abstract: The distinct preferences between goal-directed and habit-directed behaviors involve numerous neurodegenerative and psychiatric disorders. Chronic stress during adulthood biases behavior toward habit-oriented strategies. However, it remains to be studied how adolescence, as a stage in… read more here.
Keywords: stress; goal directed; striatum; chronic unpredictable ... See more keywords
Highly Sensitive Dopamine Detection Using a Bespoke Functionalised Carbon Nanotube Microelectrode array
Sign Up to like & getrecommendations! Published in 2017 at "Electroanalysis"
DOI: 10.1002/elan.201700248
Abstract: Understanding how the brain works requires developing advanced tools that allow measurement of bioelectrical and biochemical signals, including how they propagate between neurons. The introduction of nanomaterials as electrode materials has improved the impedance and… read more here.
Keywords: detection; carbon nanotube; dopamine; microelectrode ... See more keywords
Dopamine‐imprinted monolithic column for capillary electrochromatography
Sign Up to like & getrecommendations! Published in 2017 at "ELECTROPHORESIS"
DOI: 10.1002/elps.201700228
Abstract: A dopamine‐imprinted monolithic column was prepared and used in capillary electrochromatography as stationary phase for the first time. Dopamine was selectively separated from aqueous solution containing the competitor molecule norepinephrine, which is similar in size… read more here.
Keywords: capillary electrochromatography; dopamine imprinted; dopamine; monolithic column ... See more keywords
Dopamine elevates and lowers astroglial Ca2+ through distinct pathways depending on local synaptic circuitry
Sign Up to like & getrecommendations! Published in 2017 at "Glia"
DOI: 10.1002/glia.23103
Abstract: Whilst astrocytes in culture invariably respond to dopamine with cytosolic Ca2+ rises, the dopamine sensitivity of astroglia in situ and its physiological roles remain unknown. To minimize effects of experimental manipulations on astroglial physiology, here… read more here.
Keywords: dopamine elevates; elevates lowers; dopamine; ca2 ... See more keywords
Conformational and electronic study of dopamine interacting with the D2 dopamine receptor
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Computational Chemistry"
DOI: 10.1002/jcc.26361
Abstract: We report an exhaustive conformational and electronic study on dopamine (DA) interacting with the D2 dopamine receptor (D2DR). For the first time, the complete surface of the conformational potential energy of the complex DA/D2DR is… read more here.
Keywords: electronic study; dopamine; study dopamine; study ... See more keywords