Dopamine-beta-hydroxylase 19-bp insertion/deletion polymorphism affects medication overuse in patients with chronic migraine
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DOI: 10.1007/s10072-019-03865-9
Abstract: Dopamine-beta-hydroxylase (DBH) enzyme activity is modulated at the genetic level by the presence of several polymorphisms. Among these, the 19-bp insertion/deletion (I/D) polymorphism (rs72393728/rs141116007) was investigated in several genetic association studies for its correlation with… read more here.
Keywords: migraine; medication overuse; dopamine beta; chronic migraine ... See more keywords
Dopamine beta‐hydroxylase and its genetic variants in human health and disease
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Neurochemistry"
DOI: 10.1111/jnc.14893
Abstract: Dopamine beta‐hydroxylase (DβH) is an essential neurotransmitter‐synthesizing enzyme that catalyzes the formation of norepinephrine (NE) from dopamine and has been extensively studied since its discovery in the 1950s. NE serves as a neurotransmitter in both… read more here.
Keywords: dopamine beta; genetic variants; dopamine; disease ... See more keywords