Dopamine-Induced Oligomers of α-Synuclein Inhibit Amyloid Fibril Growth and Show No Toxicity.
Sign Up to like & getrecommendations! Published in 2023 at "ACS chemical neuroscience"
DOI: 10.1021/acschemneuro.2c00815
Abstract: Parkinson's disease is characterized by the selective death of dopaminergic neurons in the midbrain and accumulation of amyloid fibrils composed of α-synuclein (αSyn). Current treatment involves approaches that compensate the death of dopaminergic neurons by… read more here.
Keywords: synuclein inhibit; dopamine; induced oligomers; inhibit amyloid ... See more keywords
Dopamine‐induced interactions of female mouse hypothalamic proteins with progestin receptor‐A in the absence of hormone
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Neuroendocrinology"
DOI: 10.1111/jne.12904
Abstract: Neural progestin receptors (PR) function in reproduction, neural development, neuroprotection, learning, memory and the anxiety response. In the absence of progestins, PR can be activated by dopamine (DA) in the rodent hypothalamus to elicit female… read more here.
Keywords: induced interactions; absence; interactions female; hypothalamic proteins ... See more keywords