Dopamine D1 + D3 receptor density may correlate with parkinson disease clinical features
Sign Up to like & getrecommendations! Published in 2020 at "Annals of Clinical and Translational Neurology"
DOI: 10.1002/acn3.51274
Abstract: Dopamine D2‐like receptors – mainly dopamine D2 receptors (D2R) and dopamine D3 receptors (D3R) – are believed to be greatly involved in the pathology of Parkinson disease (PD) progression. However, these receptors have not been… read more here.
Keywords: receptor density; dopamine receptors; disease; parkinson disease ... See more keywords
Blockade of dopamine D2 receptors disrupts intrahippocampal connectivity and enhances pain‐related working memory deficits in neuropathic pain rats
Sign Up to like & getrecommendations! Published in 2018 at "European Journal of Pain"
DOI: 10.1002/ejp.1186
Abstract: Dopamine (DA) is thought to be important to local hippocampal networks integrity during spatial working memory (sWM) processing. Chronic pain may contribute to deficient dopaminergic signalling, which may in turn affect cognition. However, the neural… read more here.
Keywords: blockade dopamine; receptors disrupts; dopamine receptors; working memory ... See more keywords
Posterior dopamine D2/3 receptors and brain network functional connectivity
Sign Up to like & getrecommendations! Published in 2017 at "Synapse"
DOI: 10.1002/syn.21993
Abstract: Recent studies suggest that dopaminergic tone influences resting state activity in multiple brain networks. Although dopamine receptors and transporters have been identified in the posteromedial and parietal cortices, which are linked to functional networks such… read more here.
Keywords: brain; network; dopamine receptors; functional connectivity ... See more keywords
Lack of dopamine D1 receptors in the antidepressant actions of (R)-ketamine in a chronic social defeat stress model
Sign Up to like & getrecommendations! Published in 2019 at "European Archives of Psychiatry and Clinical Neuroscience"
DOI: 10.1007/s00406-019-01012-1
Abstract: It is reported that dopamine D 1 receptors in the medial prefrontal cortex play a role in the antidepressant actions of ( R,S )-ketamine. However, its role in the antidepressant actions of ( R )-ketamine,… read more here.
Keywords: social defeat; antidepressant actions; dopamine receptors; defeat stress ... See more keywords
Increased Retinal Ganglion Cell Survival by Exogenous IL-2 Depends on IL-10, Dopamine D1 Receptors, and Classical IL-2/IL-2R Signaling Pathways.
Sign Up to like & getrecommendations! Published in 2021 at "Neurochemical research"
DOI: 10.1007/s11064-021-03313-1
Abstract: Interleukin-2 (IL-2) is a classical pro-inflammatory cytokine known to display neuroprotective roles in the central nervous system including the retina. In the present study, we investigate the molecular targets involved in the neurotrophic effect of… read more here.
Keywords: cell survival; retinal ganglion; rgc; dopamine receptors ... See more keywords
Super-resolution Microscopical Localization of Dopamine Receptors 1 and 2 in Rat Hippocampal Synaptosomes
Sign Up to like & getrecommendations! Published in 2017 at "Molecular Neurobiology"
DOI: 10.1007/s12035-017-0688-y
Abstract: Although dopamine receptors D1 and D2 play key roles in hippocampal function, their synaptic localization within the hippocampus has not been fully elucidated. In order to understand precise functions of pre- or postsynaptic dopamine receptors… read more here.
Keywords: drs; super resolution; dopamine receptors; pre postsynaptic ... See more keywords
Involvement of D1- and D2-like dopamine receptors in the dentate gyrus in the acquisition, expression, and extinction of the morphine-induced conditioned place preference in rats
Sign Up to like & getrecommendations! Published in 2018 at "Behavioural Brain Research"
DOI: 10.1016/j.bbr.2018.07.018
Abstract: HIGHLIGHTSD1‐ and D2‐like dopamine receptors in the DG are involved in the acquisition and expression of morphine‐CPP.The effect of sulpiride revealed prominent behavioral results compared to SCH23390 in both acquisition and expression phases.Blockade of D1‐… read more here.
Keywords: morphine; acquisition; dopamine receptors; acquisition expression ... See more keywords
Induction of dopamine D1 and D5 receptors in R28 cells by light exposures.
Sign Up to like & getrecommendations! Published in 2017 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2017.03.099
Abstract: Dopamine is known to play an important role in the pathophysiological process of myopia development relevant to the ambient lighting, but it is still poorly understood about how lighting regulates dopamine and its interaction with… read more here.
Keywords: drd1 drd5; light exposures; r28 cells; dopamine receptors ... See more keywords
Dopamine D2 receptors mediate the increase in reinstatement of the conditioned rewarding effects of cocaine induced by acute social defeat
Sign Up to like & getrecommendations! Published in 2017 at "European Journal of Pharmacology"
DOI: 10.1016/j.ejphar.2017.01.039
Abstract: Abstract Social stress modifies the activity of brain areas involved in the rewarding effects of psychostimulants, inducing neuroadaptations in the dopaminergic mesolimbic system and modifying the sensitivity of dopamine receptors. In the present study we… read more here.
Keywords: effects cocaine; cocaine induced; dopamine receptors; rewarding effects ... See more keywords
The blockade of D1- and D2-like dopamine receptors within the dentate gyrus attenuates food deprivation stress-induced reinstatement of morphine-extinguished conditioned place preference in rats
Sign Up to like & getrecommendations! Published in 2020 at "Pharmacology Biochemistry and Behavior"
DOI: 10.1016/j.pbb.2020.172967
Abstract: The high rate of relapse to drug abuse is one of the main problems in the treatment of addiction. Stress plays an essential role in relapsing to drug abuse. The present study investigates the role… read more here.
Keywords: reinstatement; morphine; dopamine receptors; stress ... See more keywords
Characterization of the discriminative stimulus effect of quinpirole: Further evidence for functional interaction between central dopamine D1/D2-receptors
Sign Up to like & getrecommendations! Published in 2022 at "Pharmacology Biochemistry and Behavior"
DOI: 10.1016/j.pbb.2021.173314
Abstract: Dysfunction of the central dopamine D2-receptor-related network has been proposed to play a critical role in dopamine-related diseases, such as schizophrenia and drug dependence. Generally, the stimulation of dopamine D2-receptors on medium spiny neurons (MSN)… read more here.
Keywords: discriminative stimulus; dopamine; dopamine receptors; dopamine receptor ... See more keywords