D2 autoreceptor switches CB2 receptor effects on [3H]‐dopamine release in the striatum
Sign Up to like & getrecommendations! Published in 2019 at "Synapse"
DOI: 10.1002/syn.22139
Abstract: CB2 receptors (CB2R) are expressed in midbrain neurons. To evidence the control of dopamine release in dorsal striatum by CB2R, we performed experiments of [3H]‐dopamine release in dorsal striatal slices. We found a paradoxical increase… read more here.
Keywords: dopamine release; effect; cb2r; autoreceptor switches ... See more keywords
Amphetamine-Induced Striatal Dopamine Release Measured With an Agonist Radiotracer in Schizophrenia
Sign Up to like & getrecommendations! Published in 2018 at "Biological Psychiatry"
DOI: 10.1016/j.biopsych.2017.11.032
Abstract: BACKGROUND Receptor imaging studies have reported increased amphetamine-induced dopamine release in subjects with schizophrenia (SCH) relative to healthy control subjects (HCs). A limitation of these studies, performed with D2/3 antagonist radiotracers, is the failure to… read more here.
Keywords: bpnd; 11c npa; amphetamine induced; dopamine release ... See more keywords
l-DOPA promotes striatal dopamine release through D1 receptors and reversal of dopamine transporter
Sign Up to like & getrecommendations! Published in 2021 at "Brain Research"
DOI: 10.1016/j.brainres.2021.147583
Abstract: Previous studies have pointed out that L-DOPA can interact with D1 or D2 receptors independent of its conversion to endogenous dopamine. The present study was set to investigate whether L-DOPA modulates dopamine release from striatal… read more here.
Keywords: dopamine release; sch23390 binding; dopa; transporter ... See more keywords
Activity-dependent somatodendritic dopamine release in the substantia nigra autoinhibits the releasing neuron
Sign Up to like & getrecommendations! Published in 2021 at "Cell reports"
DOI: 10.1016/j.celrep.2021.108951
Abstract: SUMMARY Somatodendritic dopamine (DA) release from midbrain DA neurons activates D2 autoreceptors on these cells to regulate their activity. However, the source of autoregulatory DA remains controversial. Here, we test the hypothesis that D2 autoreceptors… read more here.
Keywords: somatodendritic dopamine; dopamine release; substantia nigra; activity ... See more keywords
Role of voltage-gated calcium channels on striatal dopamine release induced by inorganic mercury in freely moving rats.
Sign Up to like & getrecommendations! Published in 2018 at "Environmental toxicology and pharmacology"
DOI: 10.1016/j.etap.2018.02.005
Abstract: The possible role of voltage-sensitive calcium channels (VSCC) activation on the HgCl2-induced dopamine release was investigated using selective VSCC blockers and the dopamine levels were measured by HPLC from samples obtained by in vivo brain… read more here.
Keywords: dopamine release; calcium channels; role voltage; release induced ... See more keywords
Effects of a combination of 3,4-methylenedioxymeth amphetamine and caffeine on real time stimulated dopamine release in the rat striatum: Studies using fast cyclic voltammetry
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Neuroscience Methods"
DOI: 10.1016/j.jneumeth.2017.08.026
Abstract: It is well documented that caffeine exacerbates the hyperthermia associated with acute exposure to 3,4-methylenedioxymethamphetamine (MDMA) in rats. Previous reports have also indicated that MDMA-related enhancement of dopamine release is exacerbated in the presence of… read more here.
Keywords: combination; dopamine release; caffeine; stimulated dopamine ... See more keywords
Blockade of M4 muscarinic receptors on striatal cholinergic interneurons normalizes striatal dopamine release in a mouse model of TOR1A dystonia
Sign Up to like & getrecommendations! Published in 2022 at "Neurobiology of Disease"
DOI: 10.1016/j.nbd.2022.105699
Abstract: Trihexyphenidyl (THP), a non-selective muscarinic receptor (mAChR) antagonist, is commonly used for the treatment of dystonia associated with TOR1A, otherwise known as DYT1 dystonia. A better understanding of the mechanism of action of THP is… read more here.
Keywords: tor1a dystonia; release; striatal dopamine; dopamine release ... See more keywords
Repeated phencyclidine disrupts nicotinic acetylcholine regulation of dopamine release in nucleus accumbens: Implications for models of schizophrenia
Sign Up to like & getrecommendations! Published in 2020 at "Neurochemistry International"
DOI: 10.1016/j.neuint.2020.104836
Abstract: Dopaminergic dysregulation in nucleus accumbens has been implicated in the origin of schizophrenia. Accumbal cholinergic interneurons exert powerful modulatory control of local dopamine function, through nicotinic receptors located on dopamine terminals. Fast-scan cyclic voltammetry in… read more here.
Keywords: phencyclidine; dopamine release; dopamine; release ... See more keywords
Possible synergies between isatin, an endogenous MAO inhibitor, and antiparkinsonian agents on the dopamine release from striatum of freely moving rats.
Sign Up to like & getrecommendations! Published in 2020 at "Neuropharmacology"
DOI: 10.1016/j.neuropharm.2020.108083
Abstract: Isatin is an endogenous indole that inhibits monoamine oxidase (MAO). When exogenously administered, it increases the striatal dopamine and acetylcholine levels and presents neuroprotective effects in the brain. Previous studies show that intrastriatal administration of… read more here.
Keywords: isatin; administration isatin; isatin endogenous; dopamine release ... See more keywords
Different adaptations of dopamine release in Nucleus Accumbens shell and core of individual alcohol drinking groups of mice
Sign Up to like & getrecommendations! Published in 2020 at "Neuropharmacology"
DOI: 10.1016/j.neuropharm.2020.108176
Abstract: Alcohol use disorder (AUD) places a tremendous burden on society, with approximately two billion alcohol users in the world. While most people drink alcohol recreationally, a subpopulation (3-5%) engages in reckless and compulsive drinking, leading… read more here.
Keywords: alcohol drinking; alcohol; individual alcohol; dopamine release ... See more keywords
Dopamine Release Impairments Accompany Locomotor and Cognitive Deficiencies in Rotenone-Treated Parkinson's Disease Model Zebrafish.
Sign Up to like & getrecommendations! Published in 2022 at "Chemical research in toxicology"
DOI: 10.1021/acs.chemrestox.2c00150
Abstract: In this work, we carried out neurochemical and behavioral analysis of zebrafish (Danio rerio) treated with rotenone, an agent used to chemically induce a syndrome resembling Parkinson's disease (PD). Dopamine release, measured with fast-scan cyclic… read more here.
Keywords: dopamine release; parkinson disease; release; locomotor ... See more keywords