Fetal growth interacts with multilocus genetic score reflecting dopamine signaling capacity to predict spontaneous sugar intake in children
Sign Up to like & getrecommendations! Published in 2018 at "Appetite"
DOI: 10.1016/j.appet.2017.10.021
Abstract: BACKGROUND We have shown that intrauterine growth restriction (IUGR) leads to increased preference for palatable foods at different ages in both humans and rodents. In IUGR rodents, altered striatal dopamine signaling associates with a preference… read more here.
Keywords: growth; genetic score; sugar intake; dopamine signaling ... See more keywords
Preliminary evidence that negative symptom severity relates to multilocus genetic profile for dopamine signaling capacity and D2 receptor binding in healthy controls and in schizophrenia.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of psychiatric research"
DOI: 10.1016/j.jpsychires.2016.11.007
Abstract: Deficits in central, subcortical dopamine (DA) signaling may underlie negative symptom severity, particularly anhedonia, in healthy individuals and in schizophrenia. To investigate these relationships, we assessed negative symptoms with the Schedule for the Assessment of… read more here.
Keywords: healthy controls; negative symptom; symptom severity; dopamine signaling ... See more keywords
A unidirectional but not uniform striatal landscape of dopamine signaling for motivational stimuli
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2117270119
Abstract: Significance Although it is undisputed that striatal dopamine plays a prominent role in motivated behavior and learning, the precise information conveyed by dopamine signals as such is under active debate. For a long time, the… read more here.
Keywords: dopamine signaling; unidirectional uniform; dopamine; landscape dopamine ... See more keywords
“Reframing” dopamine signaling at the intersection of glial networks in the aged Parkinsonian brain as innate Nrf2/Wnt driver: Therapeutical implications
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DOI: 10.1111/acel.13575
Abstract: Dopamine (DA) signaling via G protein‐coupled receptors is a multifunctional neurotransmitter and neuroendocrine–immune modulator. The DA nigrostriatal pathway, which controls the motor coordination, progressively degenerates in Parkinson's disease (PD), a most common neurodegenerative disorder (ND)… read more here.
Keywords: intersection; dopamine signaling; nrf2 wnt; inflammatory ... See more keywords
Are FXR Family Proteins Integrators of Dopamine Signaling and Glutamatergic Neurotransmission in Mental Illnesses?
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Synaptic Neuroscience"
DOI: 10.3389/fnsyn.2018.00022
Abstract: Dopamine receptors and related signaling pathways have long been implicated in pathophysiology and treatment of mental illnesses, including schizophrenia and bipolar disorder. Dopamine signaling may impact neuronal activity by modulation of glutamate neurotransmission. Recent evidence… read more here.
Keywords: integrators dopamine; fxr family; mental illnesses; family ... See more keywords
Dopamine signaling tunes spatial pattern selectivity in C. elegans
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DOI: 10.7554/elife.22896
Abstract: Animals with complex brains can discriminate the spatial arrangement of physical features in the environment. It is unknown whether such sensitivity to spatial patterns can be accomplished in simpler nervous systems that lack long-range sensory… read more here.
Keywords: spatial patterns; spatial pattern; dopamine signaling; pattern selectivity ... See more keywords