HIV Neuropathogenesis in the Presence of a Disrupted Dopamine System
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Neuroimmune Pharmacology"
DOI: 10.1007/s11481-020-09927-6
Abstract: Antiretroviral therapy (ART) has transformed HIV into a chronic condition, lengthening and improving the lives of individuals living with this virus. Despite successful suppression of HIV replication, people living with HIV (PLWH) are susceptible to… read more here.
Keywords: dopamine system; hiv; hiv neuropathogenesis; dopamine ... See more keywords
Aversion hot spots in the dopamine system
Sign Up to like & getrecommendations! Published in 2020 at "Current Opinion in Neurobiology"
DOI: 10.1016/j.conb.2020.02.002
Abstract: Through the development of optogenetics and other viral vector-based technologies, our view of the dopamine system has substantially advanced over the last decade. In particular, progress has been made in the reclassification of dopamine neurons… read more here.
Keywords: system; spots dopamine; aversion hot; dopamine system ... See more keywords
Maturation of the human striatal dopamine system revealed by PET and quantitative MRI
Sign Up to like & getrecommendations! Published in 2020 at "Nature Communications"
DOI: 10.1038/s41467-020-14693-3
Abstract: The development of the striatum dopamine (DA) system through human adolescence, a time of increased sensation seeking and vulnerability to the emergence of psychopathology, has been difficult to study due to pediatric restrictions on direct… read more here.
Keywords: system; age; dopamine; dopamine system ... See more keywords
The Circuitry of Dopamine System Regulation and its Disruption in Schizophrenia: Insights Into Treatment and Prevention.
Sign Up to like & getrecommendations! Published in 2019 at "Schizophrenia bulletin"
DOI: 10.1093/schbul/sbx199
Abstract: Despite evidence for a role of the dopamine system in the pathophysiology of schizophrenia, there has not been substantial evidence that this disorder originates from a pathological change within the dopamine system itself. Current data… read more here.
Keywords: disruption; schizophrenia; dopamine system; pathology ... See more keywords
The Relationship between the Intrarenal Dopamine System and Intrarenal Renin-angiotensin System Depending on the Renal Function
Sign Up to like & getrecommendations! Published in 2018 at "Internal Medicine"
DOI: 10.2169/internalmedicine.0994-18
Abstract: Objective The mechanisms underlying the intrarenal renin-angiotensin system (RAS) activation depend on the conditions of kidney diseases. In angiotensin II (AngII) infusion models, the circulating AngII is filtered into the renal tubular lumens, activating intrarenal… read more here.
Keywords: intrarenal ras; intrarenal dopamine; system; dopamine ... See more keywords
Dysregulation of Midbrain Dopamine System and the Pathophysiology of Schizophrenia
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Psychiatry"
DOI: 10.3389/fpsyt.2020.00613
Abstract: Dysregulation of the dopamine system is central to many models of the pathophysiology of psychosis in schizophrenia. However, emerging evidence suggests that this dysregulation is driven by the disruption of upstream circuits that provide afferent… read more here.
Keywords: schizophrenia; midbrain dopamine; dysregulation; dopamine ... See more keywords
Aberrant Dopamine System Function in the Ferrous Amyloid Buthionine (FAB) Rat Model of Alzheimer’s Disease
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24087196
Abstract: Antipsychotics increase the risk of death in elderly patients with Alzheimer’s disease (AD). Thus, there is an immediate need for novel therapies to treat comorbid psychosis in AD. Psychosis has been attributed to a dysregulation… read more here.
Keywords: dopamine; fab; model; dopamine system ... See more keywords