The novel atypical dopamine transport inhibitor CT-005404 has pro-motivational effects in neurochemical and inflammatory models of effort-based dysfunctions related to psychopathology
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DOI: 10.1016/j.neuropharm.2020.108325
Abstract: Depressed individuals suffer from effort-related motivational symptoms such as anergia and fatigue, which are resistant to treatment with many common antidepressants. While drugs that block dopamine transport (DAT) reportedly have positive motivational effects, DAT inhibitors… read more here.
Keywords: novel atypical; motivational effects; effort; dopamine transport ... See more keywords