LAUSR

About LAUSR
Donate
Contact Us

Follow us:

You are not signed in:

Sign Up!


   Articles with "dopaminergic" as a keyword



Role of paraventricular hypothalamic dopaminergic D1 receptors in food intake regulation of food‐deprived rats

Sign Up to like & get
recommendations! Published in 2018 at "European Journal of Pharmacology"

DOI: 10.1016/j.ejphar.2017.10.028

Abstract: Abstract Dopaminergic neurons play an important role on central regulatory mechanisms of feeding behavior. Dopamine receptors are distributed within the hypothalamus and densely localized in the paraventricular hypothalamic nucleus (PVN). From these ideas we postulated… read more here.

Keywords: food intake; dopaminergic; food; role ... See more keywords

Decreased expression of serum- and glucocorticoid-inducible kinase 1 (SGK1) promotes alpha-synuclein increase related with down-regulation of dopaminergic cell in the Substantia Nigra of chronic MPTP-induced Parkinsonism mice and in SH-SY5Y cells.

Sign Up to like & get
recommendations! Published in 2018 at "Gene"

DOI: 10.1016/j.gene.2018.03.086

Abstract: Parkinson's disease (PD) is a chronically progressive neurodegenerative disease, with its main pathological hallmarks being a dramatic loss of dopaminergic neurons predominantly in the Substantia Nigra (SN), and the formations of intracytoplasmic Lewy bodies and… read more here.

Keywords: mptp induced; dopaminergic; expression; regulation dopaminergic ... See more keywords
Photo from wikipedia

Epigenetic Dysregulation of Dopaminergic System by Maternal Cafeteria Diet During Early Postnatal Development

Sign Up to like & get
recommendations! Published in 2020 at "Neuroscience"

DOI: 10.1016/j.neuroscience.2019.09.016

Abstract: Dopamine is a neurotransmitter crucial for motor, motivational, and reward-related functions. Our aim was to determine the effect of a palatable maternal diet on the transcriptional regulation of dopaminergic-related genes during perinatal development of the… read more here.

Keywords: methylation; dopaminergic; early postnatal; expression ... See more keywords

Dopaminergic changes in the subgenual cingulate cortex in dementia with lewy bodies associates with presence of depression

Sign Up to like & get
recommendations! Published in 2024 at "Translational Psychiatry"

DOI: 10.1038/s41398-025-03298-3

Abstract: In addition to the core clinical features of fluctuating cognition, visual hallucinations, and parkinsonism, individuals with dementia with Lewy bodies (DLB) frequently experience chronic and debilitating major depression. Treatment of depression in DLB is hampered… read more here.

Keywords: lewy bodies; cingulate; presence; depression ... See more keywords

Striatal synaptic bioenergetic and autophagic decline in premotor experimental parkinsonism

Sign Up to like & get
recommendations! Published in 2022 at "Brain"

DOI: 10.1093/brain/awac087

Abstract: Abstract Synaptic impairment might precede neuronal degeneration in Parkinson’s disease. However, the intimate mechanisms altering synaptic function by the accumulation of presynaptic α-synuclein in striatal dopaminergic terminals before dopaminergic death occurs, have not been elucidated.… read more here.

Keywords: striatal synaptic; synaptic bioenergetic; dopaminergic terminals; death ... See more keywords

Parkinson’s disease mutant Miro1 causes mitochondrial dysfunction and dopaminergic neuron loss

Sign Up to like & get
recommendations! Published in 2025 at "Brain"

DOI: 10.1093/brain/awaf051

Abstract: Abstract The complex and heterogeneous nature of Parkinson's disease (PD) is still not fully understood. However, increasing evidence supports mitochondrial impairment as a major driver of neurodegeneration. Miro1, a mitochondrial GTPase encoded by the RHOT1… read more here.

Keywords: mutant miro1; dopaminergic; parkinson disease; miro1 ... See more keywords

[Pilot study of a new tool to optimise dopaminergic treatment in Parkinson's disease: the OPTIMIPARK questionnaire].

Sign Up to like & get
recommendations! Published in 2021 at "Revista de neurologia"

DOI: 10.33588/rn.7206.2020259

Abstract: INTRODUCTION Dopaminergic therapy is effective in Parkinson's disease (PD), but should be adjusted as neurodegeneration progresses. AIMS The aim of this study was to develop a questionnaire (OPTIMIPARK) to assess the patient's dopaminergic status and… read more here.

Keywords: optimipark questionnaire; treatment; questionnaire; dopaminergic ... See more keywords
Photo by ldxcreative from unsplash

Systematic Review of the Apomorphine Challenge Test in the Assessment of Dopaminergic Activity in Schizophrenia

Sign Up to like & get
recommendations! Published in 2023 at "Healthcare"

DOI: 10.3390/healthcare11101487

Abstract: So far, neuroendocrine studies conducted in schizophrenic patients have yielded conflicting results. Many of these discrepancies may be explained by the diversity of factors that influence the hormonal levels (at baseline and in response to… read more here.

Keywords: assessment; systematic review; test; schizophrenia ... See more keywords

Cerebroventricular Injection of Pgk1 Attenuates MPTP-Induced Neuronal Toxicity in Dopaminergic Cells in Zebrafish Brain in a Glycolysis-Independent Manner

Sign Up to like & get
recommendations! Published in 2022 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms23084150

Abstract: Parkinson’s disease (PD) is characterized by the degeneration of dopaminergic neurons. While extracellular Pgk1 (ePgk1) is reported to promote neurite outgrowth, it remains unclear if it can affect the survival of dopaminergic cells. To address… read more here.

Keywords: mptp treated; brain; dopamine; pgk1 ... See more keywords

Particulate Matter Exacerbates the Death of Dopaminergic Neurons in Parkinson’s Disease through an Inflammatory Response

Sign Up to like & get
recommendations! Published in 2022 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms23126487

Abstract: Particulate matter (PM), a component of air pollution, has been epidemiologically associated with a variety of diseases. Recent reports reveal that PM has detrimental effects on the brain. In this study, we aimed to investigate… read more here.

Keywords: matter exacerbates; parkinson disease; particulate matter; death ... See more keywords

The Dopaminergic Cells in the Median Raphe Region Regulate Social Behavior in Male Mice

Sign Up to like & get
recommendations! Published in 2024 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms25084315

Abstract: According to previous studies, the median raphe region (MRR) is known to contribute significantly to social behavior. Besides serotonin, there have also been reports of a small population of dopaminergic neurons in this region. Dopamine… read more here.

Keywords: median raphe; dopaminergic cells; dopaminergic; raphe region ... See more keywords