Role of paraventricular hypothalamic dopaminergic D1 receptors in food intake regulation of food‐deprived rats
Sign Up to like & getrecommendations! Published in 2018 at "European Journal of Pharmacology"
DOI: 10.1016/j.ejphar.2017.10.028
Abstract: Abstract Dopaminergic neurons play an important role on central regulatory mechanisms of feeding behavior. Dopamine receptors are distributed within the hypothalamus and densely localized in the paraventricular hypothalamic nucleus (PVN). From these ideas we postulated… read more here.
Keywords: food intake; dopaminergic; food; role ... See more keywords
Decreased expression of serum- and glucocorticoid-inducible kinase 1 (SGK1) promotes alpha-synuclein increase related with down-regulation of dopaminergic cell in the Substantia Nigra of chronic MPTP-induced Parkinsonism mice and in SH-SY5Y cells.
Sign Up to like & getrecommendations! Published in 2018 at "Gene"
DOI: 10.1016/j.gene.2018.03.086
Abstract: Parkinson's disease (PD) is a chronically progressive neurodegenerative disease, with its main pathological hallmarks being a dramatic loss of dopaminergic neurons predominantly in the Substantia Nigra (SN), and the formations of intracytoplasmic Lewy bodies and… read more here.
Keywords: mptp induced; dopaminergic; expression; regulation dopaminergic ... See more keywords
Epigenetic Dysregulation of Dopaminergic System by Maternal Cafeteria Diet During Early Postnatal Development
Sign Up to like & getrecommendations! Published in 2020 at "Neuroscience"
DOI: 10.1016/j.neuroscience.2019.09.016
Abstract: Dopamine is a neurotransmitter crucial for motor, motivational, and reward-related functions. Our aim was to determine the effect of a palatable maternal diet on the transcriptional regulation of dopaminergic-related genes during perinatal development of the… read more here.
Keywords: methylation; dopaminergic; early postnatal; expression ... See more keywords
Striatal synaptic bioenergetic and autophagic decline in premotor experimental parkinsonism
Sign Up to like & getrecommendations! Published in 2022 at "Brain"
DOI: 10.1093/brain/awac087
Abstract: Abstract Synaptic impairment might precede neuronal degeneration in Parkinson’s disease. However, the intimate mechanisms altering synaptic function by the accumulation of presynaptic α-synuclein in striatal dopaminergic terminals before dopaminergic death occurs, have not been elucidated.… read more here.
Keywords: striatal synaptic; synaptic bioenergetic; dopaminergic terminals; death ... See more keywords
[Pilot study of a new tool to optimise dopaminergic treatment in Parkinson's disease: the OPTIMIPARK questionnaire].
Sign Up to like & getrecommendations! Published in 2021 at "Revista de neurologia"
DOI: 10.33588/rn.7206.2020259
Abstract: INTRODUCTION Dopaminergic therapy is effective in Parkinson's disease (PD), but should be adjusted as neurodegeneration progresses. AIMS The aim of this study was to develop a questionnaire (OPTIMIPARK) to assess the patient's dopaminergic status and… read more here.
Keywords: optimipark questionnaire; treatment; questionnaire; dopaminergic ... See more keywords
Systematic Review of the Apomorphine Challenge Test in the Assessment of Dopaminergic Activity in Schizophrenia
Sign Up to like & getrecommendations! Published in 2023 at "Healthcare"
DOI: 10.3390/healthcare11101487
Abstract: So far, neuroendocrine studies conducted in schizophrenic patients have yielded conflicting results. Many of these discrepancies may be explained by the diversity of factors that influence the hormonal levels (at baseline and in response to… read more here.
Keywords: assessment; systematic review; test; schizophrenia ... See more keywords
Cerebroventricular Injection of Pgk1 Attenuates MPTP-Induced Neuronal Toxicity in Dopaminergic Cells in Zebrafish Brain in a Glycolysis-Independent Manner
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23084150
Abstract: Parkinson’s disease (PD) is characterized by the degeneration of dopaminergic neurons. While extracellular Pgk1 (ePgk1) is reported to promote neurite outgrowth, it remains unclear if it can affect the survival of dopaminergic cells. To address… read more here.
Keywords: mptp treated; brain; dopamine; pgk1 ... See more keywords
Particulate Matter Exacerbates the Death of Dopaminergic Neurons in Parkinson’s Disease through an Inflammatory Response
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23126487
Abstract: Particulate matter (PM), a component of air pollution, has been epidemiologically associated with a variety of diseases. Recent reports reveal that PM has detrimental effects on the brain. In this study, we aimed to investigate… read more here.
Keywords: matter exacerbates; parkinson disease; particulate matter; death ... See more keywords
Serotonergic Neurotransmission System Modulator, Vortioxetine, and Dopaminergic D2/D3 Receptor Agonist, Ropinirole, Attenuate Fibromyalgia-Like Symptoms in Mice
Sign Up to like & getrecommendations! Published in 2021 at "Molecules"
DOI: 10.3390/molecules26082398
Abstract: Fibromyalgia is a disease characterized by lowered pain threshold, mood disorders, and decreased muscular strength. It results from a complex dysfunction of the nervous system and due to unknown etiology, its diagnosis, treatment, and prevention… read more here.
Keywords: vortioxetine; system; dopaminergic; like symptoms ... See more keywords