Altered urinary tetrahydroisoquinoline derivatives in patients with Tourette syndrome: reflection of dopaminergic hyperactivity?
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Neural Transmission"
DOI: 10.1007/s00702-020-02289-6
Abstract: Tetrahydroisoquinolines (TIQs) such as salsolinol (SAL), norsalsolinol (NSAL) and their methylated derivatives N-methyl-norsalsolinol (NMNSAL) and N -methyl-salsolinol (NMSAL), modulate dopaminergic neurotransmission and metabolism in the central nervous system. Dopaminergic neurotransmission is thought to play an… read more here.
Keywords: two way; nsal; way anova; hyperactivity ... See more keywords
Cuprizone-induced dopaminergic hyperactivity and locomotor deficit in zebrafish larvae
Sign Up to like & getrecommendations! Published in 2022 at "Brain Research"
DOI: 10.2139/ssrn.3970449
Abstract: Cuprizone (CPZ) is a copper-chelator and toxic to mitochondria. Recent studies have shown oligodendrocyte (OL) loss and demyelination along with dopamine (DA) increase and behavioral abnormalities in CPZ-exposed mice, demonstrating its application in schizophrenia research.… read more here.
Keywords: cpz; hyperactivity locomotor; zebra fish; locomotor deficit ... See more keywords