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Published in 2019 at "Journal of Comparative Neurology"
DOI: 10.1002/cne.24793
Abstract: Whereas our understanding of the dopaminergic system in mammals allows for a distinction between ventral tegmental area (VTA) and substantia nigra pars compacta (SNc), no clear evidence for separate structures in anamniotes has been presented…
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Keywords:
vta;
system;
dopaminergic system;
anuran amphibians ... See more keywords
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Published in 2017 at "European Journal of Nuclear Medicine and Molecular Imaging"
DOI: 10.1007/s00259-017-3664-x
Abstract: PurposeCervical dystonia (CD) is associated with tremor/jerks (50%) and psychiatric complaints (17–70%). The dopaminergic system has been implicated in the pathophysiology of CD in animal and imaging studies. Dopamine may be related to the motor…
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Keywords:
system;
dopaminergic system;
bpnd;
dystonia ... See more keywords
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Published in 2022 at "Behavioural Brain Research"
DOI: 10.1016/j.bbr.2022.113888
Abstract: Autism is a complex neurodevelopmental disease that may be caused by genetic and environmental factors, that are incompletely understood. Overactivation of dopaminergic receptors can lead to autistic-like behavior. β-arrestin2 (Arrb2) is a scaffolding protein of…
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Keywords:
system;
erk signaling;
signaling pathway;
like behavior ... See more keywords
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Published in 2017 at "Pharmacology Biochemistry and Behavior"
DOI: 10.1016/j.pbb.2017.01.005
Abstract: Abstract Changes in the expression of the dopamine transporter (DAT), or the sensitivity of dopamine receptors, are associated with aging and substance abuse and may underlie some of the symptoms common to both conditions. In…
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Keywords:
dopaminergic system;
anxiety;
anxiety young;
anxiety like ... See more keywords
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Published in 2017 at "Scientific Reports"
DOI: 10.1038/srep45741
Abstract: Clinical studies report significant increases in acrolein (an α,β-unsaturated aldehyde) in the substantia nigra (SN) of patients with Parkinson’s disease (PD). In the present study, acrolein-induced neurotoxicity in the nigrostriatal dopaminergic system was investigated by…
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Keywords:
nigrostriatal dopaminergic;
acrolein induced;
synuclein aggregation;
dopaminergic system ... See more keywords
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Published in 2022 at "Addiction Biology"
DOI: 10.1111/adb.13179
Abstract: Dysregulation of dopamine transporters (DAT) within the dopaminergic system is an important biomarker of cocaine exposure. Depending on cocaine amount in‐taken, one‐time exposure in rats could lead to most (>95% of total) of DAT translocating…
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Keywords:
dopaminergic system;
exposure;
cocaine;
recovery ... See more keywords
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Published in 2020 at "Experimental Physiology"
DOI: 10.1113/ep088537
Abstract: What is the central question of this study? How does spinal cord injury affect prefrontal cortex function and the expression of dopamine receptors? What is the main finding and its importance? Spinal cord injury impaired…
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Keywords:
system role;
role working;
prefrontal dopaminergic;
cord ... See more keywords
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Published in 2018 at "International Journal of Toxicology"
DOI: 10.1177/1091581817753607
Abstract: Tramadol (TR) is a synthetic analgesic drug with central function that can induce seizures even at therapeutic doses. The exact mechanism of TR effect on seizure generation is not clear, but inhibition of the serotonin…
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Keywords:
system;
dopaminergic system;
system seizure;
oxidative damage ... See more keywords
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Published in 2017 at "Experimental Animals"
DOI: 10.1538/expanim.16-0105
Abstract: In earlier ex vivo studies, we reported the biphasic effect of a methanolic extract of unripe Morinda citrifolia fruit (MMC) on dopamine-induced contractility in isolated rat vas deferens preparations. The present in vivo study was…
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Keywords:
effect;
fruit;
biphasic effect;
dopaminergic system ... See more keywords
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Published in 2017 at "Current pharmaceutical design"
DOI: 10.2174/1381612823666170111144340
Abstract: Anhedonia, characterized by a loss of interest and/or pleasure in previously enjoyable activities, is an important diagnostic criterion of Major Depressive Disorder (MDD). Converging evidence implicates a causal relationship between proinflammatory cytokines and behavioural disturbances…
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Keywords:
proinflammatory;
dopaminergic system;
proinflammatory cytokines;
role proinflammatory ... See more keywords
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Published in 2019 at "Frontiers in Behavioral Neuroscience"
DOI: 10.3389/fnbeh.2019.00184
Abstract: In male rats, copulation to satiety induces a long-lasting sexual inhibitory state, considered to rely on a decreased sexual motivation. Dopaminergic transmission at the mesolimbic system plays a central role in the regulation of male…
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Keywords:
system;
dopaminergic system;
sexual motivation;
satiety ... See more keywords