Degradable cationic polyesters via ring-opening copolymerization of valerolactones as nanocarriers for the gene delivery.
Sign Up to like & getrecommendations! Published in 2021 at "Bioorganic chemistry"
DOI: 10.1016/j.bioorg.2021.105299
Abstract: The development of cationic polymers as non-viral gene vectors has been hurdled by their high toxicity, thus degradable and biocompatible polymers are urgently demanded. Herein, five polyesters (B3a-B3e) were synthesized based on the ring-opening copolymerization… read more here.
Keywords: dope; ring opening; cationic polyesters; opening copolymerization ... See more keywords
Improving membrane distillation performance: Morphology optimization of hollow fiber membranes with selected non-solvent in dope solution.
Sign Up to like & getrecommendations! Published in 2019 at "Chemosphere"
DOI: 10.1016/j.chemosphere.2019.05.049
Abstract: This study aimed at improving membrane distillation (MD) performance by mixing various non-solvents (NSs) in polymer dope solutions. The effect of each NS on the inner structure and surface morphology of hollow fiber (HF) membrane… read more here.
Keywords: dope; improving membrane; morphology; performance ... See more keywords
DOPE: D-Optimal Pooling Experimental design with application for SARS-CoV-2 screening
Sign Up to like & getrecommendations! Published in 2021 at "Journal of the American Medical Informatics Association : JAMIA"
DOI: 10.1093/jamia/ocab169
Abstract: Abstract Objective Testing individuals for the presence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the pathogen causing the coronavirus disease 2019 (COVID-19), is crucial for curtailing transmission chains. Moreover, rapidly testing many potentially infected… read more here.
Keywords: dope; pooling strategies; experimental design; dope optimal ... See more keywords
Abstract 1997: 2C5 antibody modified dendrimer-based mixed micelles for the treatment of multidrug resistant cancers
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-1997
Abstract: Purpose: A major hurdle in chemotherapy is multidrug resistance (MDR) observed in tumors. Downregulation of efflux proteins such as P-glycoprotein (P-gp) using small interfering RNA (siRNA) can be an effective way to treat resistant tumors.… read more here.
Keywords: dendrimer micelles; dendrimer; mixed dendrimer; 2c5 antibody ... See more keywords
Conjugated nanoliposome with the HER2/neu-derived peptide GP2 as an effective vaccine against breast cancer in mice xenograft model
Sign Up to like & getrecommendations! Published in 2017 at "PLoS ONE"
DOI: 10.1371/journal.pone.0185099
Abstract: One of the challenging issues in vaccine development is peptide and adjuvant delivery into target cells. In this study, we developed a vaccine and therapeutic delivery system to increase cytotoxic T lymphocyte (CTL) response against… read more here.
Keywords: dope; her2 neu; gp2; dope mpl ... See more keywords
DOPE++: 6D pose estimation algorithm for weakly textured objects based on deep neural networks
Sign Up to like & getrecommendations! Published in 2022 at "PLoS ONE"
DOI: 10.1371/journal.pone.0269175
Abstract: This paper focuses on 6D pose estimation for weakly textured targets from RGB-D images. A 6D pose estimation algorithm (DOPE++) based on a deep neural network for weakly textured objects is proposed to solve the… read more here.
Keywords: weakly textured; network; pose estimation; estimation ... See more keywords
Evaluation of Immune Response against Leishmaniasis in BALB/c Mice Immunized with Cationic DOTAP/DOPE/CHOL Liposomes Containing Soluble Leishmania major Antigens
Sign Up to like & getrecommendations! Published in 2019 at "Iranian Journal of Parasitology"
DOI: 10.18502/ijpa.v14i1.719
Abstract: Background: Whole killed Leishmania vaccine reached phase III clinical trials but failed to display significant efficacy in human mainly due to limited Th1 inducer adjuvant. Liposomes consisting of 1, 2-dioleoyl-3trimethylammonium-propane (DOTAP) bearing an inherent adjuvanticity… read more here.
Keywords: mice; response; dotap; sla ... See more keywords
HA-DOPE-Modified Honokiol-Loaded Liposomes Targeted Therapy for Osteosarcoma
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Nanomedicine"
DOI: 10.2147/ijn.s371934
Abstract: Purpose Osteosarcoma (OS) is the most common bone cancer with a high risk of metastasis, high growth rate, and poor prognosis. Honokiol (HNK) is a general ingredient of traditional Chinese medicine, with a potential anti-tumor… read more here.
Keywords: lips hnk; loaded liposomes; dope lips; tumor ... See more keywords
Preparation and Characterization of Polymeric-Hybrid PES/TiO2 Hollow Fiber Membranes for Potential Applications in Water Treatment
Sign Up to like & getrecommendations! Published in 2017 at "Fibers"
DOI: 10.3390/fib5020014
Abstract: In this work, poly(ethersulfone) (PES) ultrafiltration (UF) hollow fibers (HF) were modified by introducing TiO2 nanoparticles (TiO2-NPs) in the polymeric dope, to endow them with photocatalytic properties. Different dope compositions and spinning conditions for producing… read more here.
Keywords: dope; water; characterization polymeric; polymeric hybrid ... See more keywords
Open Pore Ultrafiltration Hollow Fiber Membrane Fabrication Method via Dual Pore Former with Dual Dope Solution Phase
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DOI: 10.3390/membranes12111140
Abstract: Hollow-fiber membranes are widely used in various fields of membrane processes because of their numerous properties, e.g., large surface area, high packing density, mass production with uniform quality, obvious end-of-life indicators, and so on. However,… read more here.
Keywords: fiber membranes; hollow fiber; membrane; pore ... See more keywords
Co-Delivery of siRNA and Chemotherapeutic Drug Using 2C5 Antibody-Targeted Dendrimer-Based Mixed Micelles for Multidrug Resistant Cancers
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics14071470
Abstract: Multidrug resistance (MDR) observed in tumors significantly hinders the efficacy of chemotherapy. Downregulation of efflux proteins, such as P-glycoprotein (P-gp), using small interfering RNA (siRNA) can be an effective way to minimize the resistance in… read more here.
Keywords: dendrimer; delivery sirna; sirna chemotherapeutic; drug ... See more keywords