Outcomes After Treatment With Cobimetinib in Patients With Rosai-Dorfman Disease Based on KRAS and MEK Alteration Status.
Sign Up to like & getrecommendations! Published in 2022 at "JAMA oncology"
DOI: 10.1001/jamaoncol.2022.4432
Abstract: Importance Rosai-Dorfman disease (RDD) is a rare histiocytic neoplasm with recent studies showing alterations in the MAPK pathway, most commonly in the KRAS and MEK genes in about 40% of patients. Reports on the use… read more here.
Keywords: kras mek; treatment cobimetinib; dorfman disease; rosai dorfman ... See more keywords
Rosai–Dorfman Disease: A Rare Clinicopathological Presentation and Review of the Literature
Sign Up to like & getrecommendations! Published in 2020 at "Head and Neck Pathology"
DOI: 10.1007/s12105-020-01183-7
Abstract: Rosai–Dorfman disease (RDD) is a rare and self-limiting disease process that presents most commonly in young patients as massive, painless, cervical lymphadenopathy. Extranodal involvement may also occur. Histopathologic evaluation is the main diagnostic modality. We… read more here.
Keywords: presentation; cervical lymphadenopathy; rosai dorfman; disease ... See more keywords
A comprehensive assessment of cutaneous Rosai-Dorfman disease.
Sign Up to like & getrecommendations! Published in 2019 at "Annals of diagnostic pathology"
DOI: 10.1016/j.anndiagpath.2019.02.004
Abstract: BACKGROUND Cutaneous Rosai-Dorfman (CRD) disease is a rare entity that is characterized by histiocytic proliferation in the skin. The disease has been reported to exhibit different clinical profiles and occasionally confounding histologic features that may… read more here.
Keywords: cutaneous rosai; dorfman disease; disease; rosai dorfman ... See more keywords
Rosai‐Dorfman Disease: Case Report of an Unusual Testicular Involvement and Review of Literature
Sign Up to like & getrecommendations! Published in 2018 at "Clinical Genitourinary Cancer"
DOI: 10.1016/j.clgc.2018.03.008
Abstract: Rosai-Dorfman disease is an idiopathic nonmalignant histiocytosis, first described in 1969, commonly affecting childhood. The typical presentation is with fever, leukocytosis, and nonpainful cervical lymphadenopathy. Extranodal manifestation is described in adulthood in up to 25%… read more here.
Keywords: involvement; dorfman disease; rosai dorfman; disease ... See more keywords
Rosai dorfman disease: A rare presentation of primary ureteral involvement with concurrent sarcoidosis
Sign Up to like & getrecommendations! Published in 2020 at "Urology Case Reports"
DOI: 10.1016/j.eucr.2020.101251
Abstract: Rosai-Dorfman disease is a rare condition with poorly understood pathogenesis at this time. Although it often involves the lymph nodes, it can present nearly anywhere at extranodal sites. Patients are frequently asymptomatic, but surgical debulking… read more here.
Keywords: disease rare; dorfman disease; rosai dorfman; presentation ... See more keywords
[Rosai-Dorfman disease: Sinusal histiocytosis with massive lymphadenopathy].
Sign Up to like & getrecommendations! Published in 2017 at "Presse medicale"
DOI: 10.1016/j.lpm.2016.01.015
Abstract: Rosai-Dorfman sinusal histiocytosis is a benign histiocytic disorder presenting as large lymphadenopathies, mostly in the cervical area. Visceral involvement is not unusual. The diagnosis is based on histologic findings, showing intrasinusoidal histiocytic infiltration with pathognomonic… read more here.
Keywords: disease sinusal; sinusal histiocytosis; rosai dorfman; dorfman disease ... See more keywords
Rosai-Dorfman disease mimicking cavernous hemangioma: a case report.
Sign Up to like & getrecommendations! Published in 2022 at "Orbit"
DOI: 10.1080/01676830.2022.2055086
Abstract: A 31-year-old female presented to the clinic with a 2 year history of proptosis of the right eye. She was diagnosed with cavernous hemangioma during her initial ophthalmologic consult and was advised monitoring. However, after… read more here.
Keywords: dorfman disease; rosai dorfman; report; cavernous hemangioma ... See more keywords
Strong Coexpression of Transcription Factors PU.1 and Oct-2 in Rosai-Dorfman Disease.
Sign Up to like & getrecommendations! Published in 2022 at "American journal of clinical pathology"
DOI: 10.1093/ajcp/aqac119
Abstract: OBJECTIVES Rosai-Dorfman disease (RDD) is a rare disorder characterized by the accumulation of large S100 protein-positive histiocytes that typically exhibit emperipolesis. The recently reported expression of Oct-2 in RDD histiocytes led us to explore whether… read more here.
Keywords: strong coexpression; rdd; dorfman disease; rosai dorfman ... See more keywords
How I Diagnose Rosai-Dorfman Disease.
Sign Up to like & getrecommendations! Published in 2023 at "American journal of clinical pathology"
DOI: 10.1093/ajcp/aqad047
Abstract: OBJECTIVES Rosai-Dorfman disease (RDD) is one of 3 major types of histiocytosis, along with Erdheim-Chester disease and Langerhans cell histiocytosis. While historically, RDD was considered a benign self-limited condition, current data show MAPK/ERK pathway mutations… read more here.
Keywords: disease; rdd; dorfman disease; rosai dorfman ... See more keywords
Successful Treatment of Cutaneous Rosai-Dorfman Disease With Pulsed Dye Laser.
Sign Up to like & getrecommendations! Published in 2020 at "Dermatologic Surgery"
DOI: 10.1097/dss.0000000000001798
Abstract: A 70-year-old woman presented with 1-month history of a cutaneous lesion located on the philtrum. Physical examination revealed a solitary erythematous plaque with a beaded appearance (Figure 1A). The lesion began as a small papule… read more here.
Keywords: successful treatment; rosai dorfman; dorfman disease; treatment ... See more keywords
Radiological and clinical findings of isolated meningeal Rosai–Dorfman disease of the central nervous system
Sign Up to like & getrecommendations! Published in 2019 at "Medicine"
DOI: 10.1097/md.0000000000015365
Abstract: Abstract Rosai–Dorfman disease (RDD) with isolated central nervous system (CNS) involvement is an extremely rare disease. Most RDD of the CNS present as dural-based mass mimicking meningioma and other common lesions, which makes preoperative accurate… read more here.
Keywords: central nervous; dorfman disease; rosai dorfman; nervous system ... See more keywords