The dormant cancer cell life cycle
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DOI: 10.1038/s41568-020-0263-0
Abstract: The success of targeted therapies and immunotherapies has created optimism that cancers may be curable. However, not all patients respond, drug resistance is common and many patients relapse owing to dormant cancer cells. These rare… read more here.
Keywords: life cycle; cancer cell; cancer; cell ... See more keywords
BEX2 suppresses mitochondrial activity and is required for dormant cancer stem cell maintenance in intrahepatic cholangiocarcinoma
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-78539-0
Abstract: Cancer stem cells (CSCs) define a subpopulation of cancer cells that are resistant to therapy. However, little is known of how CSC characteristics are regulated. We previously showed that dormant cancer stem cells are enriched… read more here.
Keywords: cancer stem; cholangiocarcinoma; dormant cancer; cancer ... See more keywords