Metastasis 'systems' biology: how are macro-environmental signals transmitted into microenvironmental cues for disseminated tumor cells?
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DOI: 10.1016/j.ceb.2017.06.002
Abstract: Disseminated breast tumor cells reside on or near stable microvascular endothelium. Currently, the cues that disrupt DTC dormancy and facilitate outgrowth are largely unknown. This article explores the hypothesis that specific patient lifestyle exposures (e.g.,… read more here.
Keywords: disseminated tumor; dormant niche; tumor cells; metastasis ... See more keywords