A high content screening assay for identifying inhibitors against active and dormant state intracellular Mycobacterium tuberculosis.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of microbiological methods"
DOI: 10.1016/j.mimet.2019.105687
Abstract: The antitubercular drug development pipeline could start with an in vitro investigation of several compounds to examine their effect on active and dormant state Mycobacterium tuberculosis (Mtb). However, in vitro screening of dormant state bacilli… read more here.
Keywords: state; dormant state; active dormant; state intracellular ... See more keywords
Mechanical stress accompanied with nuclear rotation is involved in the dormant state of mouse oocytes
Sign Up to like & getrecommendations! Published in 2019 at "Science Advances"
DOI: 10.1126/sciadv.aav9960
Abstract: Compression keeps oocytes dormant. The most immature oocytes remain dormant in primordial follicles in the ovary, ensuring the longevity of female reproductive life. Despite its biological and clinical importance, knowledge of mechanisms regulating the dormant… read more here.
Keywords: state; mechanical stress; primordial follicles; dormant state ... See more keywords
The Genetic Basis of Dormancy and Awakening in Cutaneous Metastatic Melanoma
Sign Up to like & getrecommendations! Published in 2022 at "Cancers"
DOI: 10.3390/cancers14092104
Abstract: Simple Summary Advanced malignant melanoma still has a poor prognosis. Mortality is closely associated with tumor recurrence, which, as with other types of cancer, can occur after long periods of clinical remission. Clinical latency is… read more here.
Keywords: dormant state; melanoma; tumor cells; tumor ... See more keywords