Comparison of inhaled mannitol/dornase alfa combination and daily dornase alfa alone in children with cystic fibrosis.
Sign Up to like & getrecommendations! Published in 2021 at "Pediatric pulmonology"
DOI: 10.1002/ppul.25740
Abstract: OBJECTIVES Inhaled recombinant human deoxyribonuclease (dornase alfa) and osmotic agents such as inhaled mannitol are used for improving the clearance of secretions of cystic fibrosis (CF) patients. We aimed to evaluate the long term clinical… read more here.
Keywords: dpi mannitol; dornase alfa; dornase; treatment ... See more keywords
Dornase alfa during lower respiratory tract infection post‐lung transplantation: a randomized controlled trial
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DOI: 10.1111/tri.13400
Abstract: Lung transplant (LTx) recipients are at risk of lower respiratory tract infection (LRTI), while altered physiology may lead to difficulty clearing sputum. Mucoactive agents alter sputum properties and facilitate mucociliary clearance; however, there are no… read more here.
Keywords: dornase alfa; lower respiratory; respiratory tract; post ... See more keywords
Non-Randomized Trial of Dornase Alfa for Acute Respiratory Distress Syndrome Secondary to Covid-19
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2021.714833
Abstract: Background The most severe cases of Coronavirus-Disease-2019 (COVID-19) develop into Acute Respiratory Distress Syndrome (ARDS). It has been proposed that oxygenation may be inhibited by extracellular deoxyribonucleic acid (DNA) in the form of neutrophil extracellular… read more here.
Keywords: dornase alfa; trial; secondary covid; dna ... See more keywords