Small Molecules Enhance Reprogramming of Adult Human Dermal Fibroblasts to Dorsal Forebrain Precursor Cells.
Sign Up to like & getrecommendations! Published in 2021 at "Stem cells and development"
DOI: 10.1089/scd.2021.0130
Abstract: The development of human cell-based platforms for disease modelling, drug discovery and regenerative therapy rely on robust and practical methods to derive high yields of relevant neuronal subtypes. Direct reprogramming strategies have sought to provide… read more here.
Keywords: dorsal forebrain; precursor; adult human; cell ... See more keywords
Dorsal Forebrain-Specific Deficiency of Reelin-Dab1 Signal Causes Behavioral Abnormalities Related to Psychiatric Disorders
Sign Up to like & getrecommendations! Published in 2017 at "Cerebral Cortex"
DOI: 10.1093/cercor/bhv334
Abstract: Reelin-Dab1 signaling is involved in brain development and neuronal functions. The abnormalities in the signaling through either reduction of Reelin and Dab1 gene expressions or the genomic mutations in the brain have been reported to… read more here.
Keywords: reelin dab1; deficiency reelin; dorsal forebrain; psychiatric disorders ... See more keywords