Hypoxia promotes tau hyperphosphorylation with associated neuropathology in vascular dysfunction
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DOI: 10.1016/j.nbd.2018.07.009
Abstract: BACKGROUND Hypertension-induced microvascular brain injury is a major vascular contributor to cognitive impairment and dementia. We hypothesized that chronic hypoxia promotes the hyperphosphorylation of tau and cell death in an accelerated spontaneously hypertensive stroke prone… read more here.
Keywords: dorsolateral cortex; hyperphosphorylation; vascular dysfunction; hypoxia promotes ... See more keywords