LAUSR

Crystal structure of Maternal Embryonic Leucine Zipper Kinase (MELK) in complex with dorsomorphin (Compound C).

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1 Published in 2019 at "Archives of biochemistry and biophysics"

DOI: 10.1016/j.abb.2019.05.014

Abstract: Maternal Embryonic Leucine Zipper Kinase (MELK) is overexpressed in various tumors which has been convincingly linked to tumor cell survival. As such, MELK became an interesting target for pharmacological intervention. In this study we present… read more here.

Keywords: maternal embryonic; leucine zipper; melk; embryonic leucine ... See more keywords