Effect of High vs Low Doses of Chloroquine Diphosphate as Adjunctive Therapy for Patients Hospitalized With Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection: A Randomized Clinical Trial.
Sign Up to like & getrecommendations! Published in 2020 at "JAMA network open"
DOI: 10.1001/jamanetworkopen.2020.8857
Abstract: Importance There is no specific antiviral therapy recommended for coronavirus disease 2019 (COVID-19). In vitro studies indicate that the antiviral effect of chloroquine diphosphate (CQ) requires a high concentration of the drug. Objective To evaluate… read more here.
Keywords: dosage group; group; coronavirus; dosage ... See more keywords
Comparative Effectiveness of Opioid Tapering or Abrupt Discontinuation vs No Dosage Change for Opioid Overdose or Suicide for Patients Receiving Stable Long-term Opioid Therapy
Sign Up to like & getrecommendations! Published in 2022 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2022.26523
Abstract: Key Points Question For patients receiving stable long-term opioid therapy compared with a stable opioid dosage, what is the association of opioid dosage tapering or abrupt discontinuation with opioid overdose or suicide? Findings In this… read more here.
Keywords: long term; term opioid; dosage; stable long ... See more keywords
Assessing the effects of solid versus liquid dosage forms of oral medications on adherence and acceptability in children
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DOI: 10.1002/14651858.cd012783
Abstract: This is a protocol for a Cochrane Review (Intervention). The objectives are as follows: To assess the effects of solid versus liquid dosage forms on adherence to and acceptability of oral medications in children. Secondary… read more here.
Keywords: solid versus; liquid dosage; versus liquid; dosage forms ... See more keywords
Defect Engineering to Achieve Wake‐up Free HfO 2 ‐Based Ferroelectrics
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DOI: 10.1002/adem.202000791
Abstract: Wake-up effect is still an obstacle in the commercialization of hafnia-based ferroelectric thin films. In this work, we investigate the effect of defects, controlled by ozone dosage, on the field cycling behavior of the atomic… read more here.
Keywords: engineering; wake effect; wake free; dosage ... See more keywords
What's in fake "Xanax"? : a dosage survey of designer benzodiazepines in counterfeit pharmaceutical tablets.
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DOI: 10.1002/dta.3119
Abstract: The identification of a range of different drugs within counterfeit benzodiazepine tablets has been widely reported, however limited information is available on the dosage of these products. A rapid dosage survey of 46 counterfeit benzodiazepine… read more here.
Keywords: counterfeit benzodiazepine; dosage survey; fake xanax; xanax dosage ... See more keywords
Genomic prediction with allele dosage information in highly polyploid species
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DOI: 10.1007/s00122-021-03994-w
Abstract: Key message Including allele, dosage can improve genomic selection in highly polyploid species under higher frequency of different heterozygous genotypic classes and high dominance degree levels. Abstract Several studies have shown how to leverage allele… read more here.
Keywords: genomic selection; dosage information; highly polyploid; allele dosage ... See more keywords
Assessment of micafungin loading dosage regimens against Candida spp. in ICU patients by Monte Carlo simulations
Sign Up to like & getrecommendations! Published in 2020 at "European Journal of Clinical Pharmacology"
DOI: 10.1007/s00228-020-02840-0
Abstract: To assess the efficacy of loading dose on micafungin by simulating different dosage regimens. A published study of micafungin in ICU patients was employed to simulate nine different dosage regimens which were sorted out three… read more here.
Keywords: auc mic; candida spp; icu patients; dosage ... See more keywords
Acute motor axonal polyneuropathy in one parkinsonian patient receiving moderate dosage of oral levodopa
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DOI: 10.1007/s10072-020-04989-z
Abstract: Recently, increased attention has been given to polyneuropathy in Parkinson’s disease (PD), with a possible causative role of levodopa (L-dopa) metabolic pathway [1, 2]. Oral L-dopa was mostly associated with a large predominance of slowly… read more here.
Keywords: dopa; motor; parkinsonian patient; dosage ... See more keywords
Selective Spectrofluorimetric Protocol for Determination of Commonly Used Gram-negative Bactericidal Drug in Combined Pharmaceutical Dosage Forms and Human Plasma.
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DOI: 10.1007/s10895-021-02862-6
Abstract: Gram-negative bacteria cause infections such as skin infection, meningitis, and pneumonia in human being. Gram-negative bacteria are highly resistant to most availaible bactericidal drugs. One of the most commonly used Gram-negative bactericidal drug is Polymyxin… read more here.
Keywords: commonly used; pms; used gram; human plasma ... See more keywords
Evaluation of the effect of torsemide on warfarin dosage requirements
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DOI: 10.1007/s11096-017-0479-6
Abstract: Background According to drug interaction databases, torsemide may potentiate the effects of warfarin. Evidence for this drug–drug interaction, however, is conflicting and the clinical significance is unknown. Objective The aim of this study is to… read more here.
Keywords: warfarin dosage; torsemide initiation; dosage; dosage requirements ... See more keywords
Impact of antithrombin III and enoxaparin dosage adjustment on prophylactic anti-Xa concentrations in trauma patients at high risk for venous thromboembolism: a randomized pilot trial
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DOI: 10.1007/s11239-021-02478-4
Abstract: The impact of antithrombin III activity (AT-III) on prophylactic enoxaparin anti-factor Xa concentration (anti-Xa) is unknown in high-risk trauma patients. So too is the optimal anti-Xa-adjusted enoxaparin dosage. This prospective, randomized, pilot study sought to… read more here.
Keywords: iii; goal; adjustment; enoxaparin ... See more keywords