Gene‐dosage effect of Pfkfb3 on monocyte/macrophage biology in atherosclerosis
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DOI: 10.1111/bph.15926
Abstract: Macrophage‐rich atherosclerotic arteries are highly active in glycolysis. PFKFB3, a key glycolytic enzyme, has emerged as a potential therapeutic target in atherosclerosis. Small‐molecule inhibitors of PFKFB3, such as 3PO and PFK158, have demonstrated efficacy in… read more here.
Keywords: dosage effect; atherosclerosis; gene dosage; macrophage ... See more keywords
High-Throughput Phenotyping (HTP) Data Reveal Dosage Effect at Growth Stages in Arabidopsis thaliana Irradiated by Gamma Rays
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DOI: 10.3390/plants9050557
Abstract: The effects of radiation dosages on plant species are quantitatively presented as the lethal dose or the dose required for growth reduction in mutation breeding. However, lethal dose and growth reduction fail to provide dynamic… read more here.
Keywords: dosage effect; effect; phenotyping htp; throughput phenotyping ... See more keywords