Traditional Chinese Medicine "Pill", an Ancient Dosage Form with Surprising Modern Pharmaceutical Characteristics.
Sign Up to like & getrecommendations! Published in 2021 at "Pharmaceutical research"
DOI: 10.1007/s11095-021-03007-x
Abstract: Currently, the use of Traditional Chinese Medicine (TCM) for healthy living in daily practice is widely accepted across the world. However, not much attention has been paid to the particular characteristics of TCM "pills", one… read more here.
Keywords: modern pharmaceutical; medicine; pill; dosage form ... See more keywords
Development of controlled release amorphous solid dispersions (CRASD) using polyvinyl acetate‐based release retarding materials: Effect of dosage form design
Sign Up to like & getrecommendations! Published in 2018 at "European Journal of Pharmaceutical Sciences"
DOI: 10.1016/j.ejps.2018.09.006
Abstract: ABSTRACT The amorphous solid dispersion (ASD) technique has been employed to formulate poorly‐soluble drugs, however, development of solid dosage forms with ASD is challenging due to the high propensity of amorphous drug to precipitate upon… read more here.
Keywords: form design; dosage form; dosage; dissolution ... See more keywords
Preparation and evaluation of a novel dosage form for onychomycosis.
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DOI: 10.1016/j.ijpharm.2016.12.055
Abstract: Onychomycosis is a common infection of the nail caused by dermatophyte affecting mostly toenails in adults being associated with limited treatment options. In this study novel dosage forms were prepared and evaluated for their suitability… read more here.
Keywords: novel dosage; dosage form; dosage; onychomycosis ... See more keywords
Film-injection as a dosage form for etomidate: Enhancing the stability of nanomedicines using solid intermediate products
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Drug Delivery Science and Technology"
DOI: 10.1016/j.jddst.2020.101541
Abstract: Abstract The colloidal stability problem is one of the major obstacles for bench-to-bedside translation of many nanomedicines. Herein, we developed a new strategy that adopted a novel dosage form called “film-injection”. Etomidate, a first-line general… read more here.
Keywords: etomidate; film injection; film; dosage form ... See more keywords
Evaluation of Differences in Dosage Form Performance of Generics using BCS-Based Biowavier Specifications and Biopharmaceutical Modeling - Case Examples Amoxicillin and Doxycycline.
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DOI: 10.1016/j.xphs.2020.04.011
Abstract: Drug products containing the antibiotics amoxicillin (500 mg as trihydrate) or doxycycline (200 mg as hyclate or monohydrate) with varying qualitative excipient composition were obtained from the German market and their biopharmaceutical properties were characterized… read more here.
Keywords: based biowaiver; form performance; bcs; bcs based ... See more keywords
The Development of Minitablets for a Pediatric Dosage Form for a Combination Therapy.
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DOI: 10.1016/j.xphs.2020.08.021
Abstract: Minitablet is an appealing option for an age-appropriate pediatric dosage form. In particular, for combination therapies where multiple active ingredients are dosed simultaneously, the use of this dosage form will enable independent adjustments of each… read more here.
Keywords: dosage; combination therapy; pediatric dosage; dosage form ... See more keywords
Applications of Machine Learning in Solid Oral Dosage Form Development.
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DOI: 10.1016/j.xphs.2021.04.013
Abstract: This review comprehensively summarizes the application of machine learning in solid oral dosage form development over the past three decades. In both academia and industry, machine learning is increasingly applied for multiple preformulation/formulation and process… read more here.
Keywords: machine; machine learning; solid oral; oral dosage ... See more keywords
Spray Drying and Particle Engineering in Dosage Form Design for Global Vaccines.
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DOI: 10.1089/jamp.2021.0056
Abstract: Vaccines are a very important tool in the effort to reduce the global burden of infectious diseases. Modern vaccines can be formulated in several ways to induce specific immunity, including through the use of live… read more here.
Keywords: dosage; spray drying; dosage form; drying particle ... See more keywords
Validated Smart Different Chromatographic Methods for Selective Quantification of Acefylline Piperazine, Phenobarbital Sodium and Methylparaben Additive in Bulk and Pharmaceutical Dosage Form.
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DOI: 10.1093/chromsci/bmac003
Abstract: Two chromatographic methods have been proposed for the simultaneous determination of acefylline piperazine (ACEF) and phenobarbital (PHENO) in presence of methylparaben as additive in pharmaceutical dosage form. The first method was thin-layer chromatography. The separation… read more here.
Keywords: phase; dosage form; pharmaceutical dosage; chromatographic methods ... See more keywords
A Novel Stability Indicating RP-HPLC Method for Simultaneous Quantification of Serdexmethylphenidate and Dexmethylphenidate in Fixed Dosage Form.
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DOI: 10.1093/chromsci/bmac011
Abstract: A simple, robust stability indicating RP-HPLC method was developed for simultaneous quantification of serdexmethyl phenidate and dexmethyl phenidate in a fixed capsule dosage form. This is the first method to be reported for simultaneous estimation… read more here.
Keywords: quantification; stability indicating; phenidate; method ... See more keywords
Development and validation of four spectrophotometric methods for assay of rebamipide and its impurity: application to tablet dosage form.
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DOI: 10.1093/jaoacint/qsab099
Abstract: BACKGROUND Rebamipide (REB) is quinolinone derivative compound, which is used for treatment of stomach ulcers. OBJECTIVE Four Spectrophotometric methods are developed for quantification of REB and its impurity and degradation product; the debenzoylated isomer of… read more here.
Keywords: four spectrophotometric; reb; spectrophotometric methods; der ... See more keywords