Application of dose-addition analyses to characterize the abuse-related effects of drug mixtures.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the experimental analysis of behavior"
DOI: 10.1002/jeab.741
Abstract: Polysubstance use makes up a majority of drug use, yet relatively few studies investigate the abuse-related effects of drug mixtures. Dose-addition analyses provide a rigorous and quantitative method to determine the nature of the interaction… read more here.
Keywords: addition; addition analyses; related effects; abuse related ... See more keywords
Dose Addition in the Induction of Craniofacial Malformations in Zebrafish Embryos Exposed to a Complex Mixture of Food-Relevant Chemicals with Dissimilar Modes of Action
Sign Up to like & getrecommendations! Published in 2022 at "Environmental Health Perspectives"
DOI: 10.1289/ehp9888
Abstract: Background: Humans are exposed to combinations of chemicals. In cumulative risk assessment (CRA), regulatory bodies such as the European Food Safety Authority consider dose addition as a default and sufficiently conservative approach. The principle of… read more here.
Keywords: craniofacial malformations; food; mixture; malformations zebrafish ... See more keywords