Comparative study of novel dosing schedules for interrupted immunotherapy for allergic rhinitis
Sign Up to like & getrecommendations! Published in 2022 at "Clinical and Translational Allergy"
DOI: 10.1002/clt2.12147
Abstract: To the Editor, Allergic rhinitis (AR) management includes allergen avoidance, pharmacotherapy, allergen‐specific immunotherapy (AIT), and patient education. AIT is currently the only curative intervention that can potentially change the natural course of allergic disease. Patients… read more here.
Keywords: injection; novel conventional; schedule; treatment ... See more keywords
Outcomes for Inappropriate Renal Dose Adjustment of Dipeptidyl Peptidase-4 Inhibitors in Patients With Type 2 Diabetes Mellitus: Population-Based Study.
Sign Up to like & getrecommendations! Published in 2019 at "Mayo Clinic proceedings"
DOI: 10.1016/j.mayocp.2019.06.010
Abstract: OBJECTIVES To estimate inappropriate dosing of dipeptidyl peptidase-4 (DPP-4) inhibitors and to assess the risk of emergency department visits, hypoglycemia, and mortality in patients with type 2 diabetes mellitus (T2DM) and chronic kidney disease (CKD)… read more here.
Keywords: dipeptidyl peptidase; adjustment; dpp inhibitor; dose adjustment ... See more keywords
Individual dose adjustment of riociguat in patients with pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension.
Sign Up to like & getrecommendations! Published in 2017 at "Respiratory medicine"
DOI: 10.1016/j.rmed.2017.05.005
Abstract: Riociguat is a soluble guanylate cyclase stimulator that has been approved for the treatment of pulmonary arterial hypertension and inoperable chronic thromboembolic pulmonary hypertension or persistent/recurrent pulmonary hypertension following pulmonary endarterectomy. Riociguat is administered using… read more here.
Keywords: pulmonary hypertension; pulmonary arterial; hypertension; dose adjustment ... See more keywords
Vortioxetine 20 mg/day in patients with major depressive disorder: updated analysis of efficacy, safety, and optimal timing of dose adjustment.
Sign Up to like & getrecommendations! Published in 2021 at "CNS spectrums"
DOI: 10.1017/s1092852921000936
Abstract: Background. Analysis of efficacy and tolerability of vortioxetine 20 mg/day, and optimal timing of dose adjustment, in patients with major depressive disorder (MDD). Methods. Pooled analysis of six randomized, fixed-dose studies of vortioxetine 5 to… read more here.
Keywords: dose adjustment; vortioxetine day; timing dose; day ... See more keywords
Starting dose and dose adjustment of non-vitamin K antagonist oral anticoagulation agents in a nationwide cohort of patients with atrial fibrillation
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-99818-4
Abstract: This study aims to provide real-world data about starting-dose of NOACs and dose-adjustment in patients with atrial fibrillation (AF). In fact, even if new oral anticoagulation agents (NOACs) have a predictable effect without need for… read more here.
Keywords: atrial fibrillation; starting dose; anticoagulation agents; dose adjustment ... See more keywords
DosOpt: A Tool for Personalized Bayesian Dose Adjustment of Vancomycin in Neonates
Sign Up to like & getrecommendations! Published in 2017 at "Therapeutic Drug Monitoring"
DOI: 10.1097/ftd.0000000000000456
Abstract: Background: Our main aim has been to design a framework to improve vancomycin dosing in neonates. This required the development and verification of a computerized dose adjustment application, DosOpt, to guide the selection. Methods: Model… read more here.
Keywords: vancomycin; model; dose adjustment; concentration ... See more keywords
Limited Sampling Strategies Supporting Individualized Dose Adjustment of Intravenous Busulfan in Children and Young Adults.
Sign Up to like & getrecommendations! Published in 2019 at "Therapeutic Drug Monitoring"
DOI: 10.1097/ftd.0000000000000700
Abstract: BACKGROUND AND AIMS Therapeutic drug monitoring (TDM) for busulfan supports dose adjustment during conditioning for stem cell transplantation. The authors aimed to develop and validate limited sampling strategies (LSS) of 4 to 5 samples for… read more here.
Keywords: sampling strategies; limited sampling; dose adjustment; busulfan ... See more keywords
Mycophenolate Mofetil Dose Adjustment in Pediatric Kidney Transplant Recipients.
Sign Up to like & getrecommendations! Published in 2023 at "Therapeutic drug monitoring"
DOI: 10.1097/ftd.0000000000001087
Abstract: BACKGROUND The Immunosuppressant Bayesian Dose Adjustment web site aids clinicians and pharmacologists involved in the care of transplant recipients; it proposes dose adjustments based on the estimated area under the concentration-time curve (AUCs). Three concentrations… read more here.
Keywords: kidney transplant; pediatric kidney; transplant recipients; adjustment ... See more keywords
Relationship between anti-Xa level achieved with prophylactic low-molecular weight heparin and venous thromboembolism in trauma patients: A systematic review and meta-analysis
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Trauma and Acute Care Surgery"
DOI: 10.1097/ta.0000000000003580
Abstract: Do anti-Xa levels effect VTE in trauma patients? Should we be targeting levels with our chemoprophylaxis? This sytematic review evaluates these questions with some surprising outcomes. BACKGROUND Trauma patients have simultaneously high venous thromboembolism (VTE)… read more here.
Keywords: vte; analysis; anti; trauma patients ... See more keywords
Can the Area Under the Curve/Trough Level Ratio Be Used to Optimize Tacrolimus Individual Dose Adjustment?
Sign Up to like & getrecommendations! Published in 2022 at "Transplantation"
DOI: 10.1097/tp.0000000000004405
Abstract: Background. The aim of this work was to evaluate, in a large data set of renal transplant recipients, the intraindividual variability of the area under the curve (AUC)/predose concentration (C0) ratio in comparison with that… read more here.
Keywords: auc; ratio; auc ratio; area curve ... See more keywords
Very tight vs. tight control: what should be the criteria for pharmacologic therapy dose adjustment in diabetes in pregnancy? Evidence from randomized controlled trials
Sign Up to like & getrecommendations! Published in 2018 at "Acta Obstetricia et Gynecologica Scandinavica"
DOI: 10.1111/aogs.13257
Abstract: There is inconclusive evidence from randomized controlled trials (RCTs) to support any specific criteria for pharmacologic therapy dose adjustment in diabetes in pregnancy. Our objective was to analyze the criteria for dose adjustment of pharmacologic… read more here.
Keywords: randomized controlled; evidence randomized; pharmacologic therapy; dose adjustment ... See more keywords