Oral Administration of Meloxicam Suppresses Low-Dose Endotoxin Challenge-Induced Pain in Thoroughbred Horses.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of equine veterinary science"
DOI: 10.1016/j.jevs.2019.03.001
Abstract: Nonsteroidal anti-inflammatory drugs such as flunixin meglumine have been used to treat signs of systemic inflammatory conditions, but it is also known to have the side effect to small intestine mucosa. It may be considered… read more here.
Keywords: pain; meloxicam; thoroughbred horses; dose endotoxin ... See more keywords
Prenatal low-dose endotoxin exposure prolongs intestinal epithelial activation after birth and contributes to necrotizing enterocolitis.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of pediatric surgery"
DOI: 10.1016/j.jpedsurg.2020.03.005
Abstract: PURPOSE To investigate the effects of low dose endotoxin on transcriptional activity in intestinal epithelium, and its role in necrotizing enterocolitis (NEC). METHODS Lipopolysaccharides (LPS) were injected into the amniotic cavity of pregnant mice under… read more here.
Keywords: low dose; dose endotoxin; prenatal low; activation ... See more keywords
Immune-enhancing neutrophils reprogrammed by subclinical low-dose endotoxin in cancer treatment
Sign Up to like & getrecommendations! Published in 2024 at "EMBO Molecular Medicine"
DOI: 10.1038/s44321-024-00100-7
Abstract: Despite the re-emergence of the pioneering “Coley’s toxin” concept in anti-cancer immune therapies highlighted by check-point inhibitors and CAR-T approaches, fundamental mechanisms responsible for the immune-enhancing efficacy of low-dose “Coley’s toxin” remain poorly understood. This… read more here.
Keywords: low dose; dose; tumor; dose endotoxin ... See more keywords