Articles with "dose enhancement" as a keyword



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Bismuth oxide nanoparticles as agents of radiation dose enhancement in intra operative radiotherapy.

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Published in 2021 at "Medical physics"

DOI: 10.1002/mp.14697

Abstract: PURPOSE Intraoperative radiotherapy (IORT) technique is an advanced radio therapeutic method used for delivery of a high single dose radiation during surgery while removing healthy tissues from the radiation field. Nowadays, growing attention is being… read more here.

Keywords: sheet spherical; bismuth oxide; oxide nanoparticles; dose enhancement ... See more keywords
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Monte Carlo simulation of dose enhancement due to silver nanoparticles implantation in brain tumor brachytherapy using a digital phantom

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Published in 2019 at "Radiation Physics and Chemistry"

DOI: 10.1016/j.radphyschem.2018.10.027

Abstract: Abstract The use of silver nanoparticles as adjuvants in cancer radiation therapy is becoming progressively well acknowledged. Based on simulation methods, we report outcomes on dose enhancement for different silver concentrations implant and different beam… read more here.

Keywords: silver nanoparticles; tumor; dose enhancement; simulation ... See more keywords
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Promising magnetic nanoradiosensitizers for combination of tumor hyperthermia and x-ray therapy: Theoretical calculation

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Published in 2021 at "Journal of Applied Physics"

DOI: 10.1063/5.0032843

Abstract: Nanoparticle (NP) assisted magnetic hyperthermia (NMH) is a clinically proven method for cancer treatment. High-Z magnetic NPs could also be a perspective object for combining hyperthermia with tumor radiosensitization. However, this application of NPs is… read more here.

Keywords: hyperthermia; promising magnetic; dose enhancement; magnetic nanoradiosensitizers ... See more keywords
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Determining dose enhancement factors of high-Z nanoparticles from simulations where lateral secondary particle disequilibrium exists.

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Published in 2019 at "Physics in medicine and biology"

DOI: 10.1088/1361-6560/ab31d4

Abstract: Nanoparticles containing high atomic number (high-Z) materials have been shown to enhance the radiobiological effectiveness of ionizing radiation. This effect is often attributed to an enhancement of the absorbed dose in the vicinity of the… read more here.

Keywords: dose enhancement; enhancement factors; secondary particle; determining dose ... See more keywords
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Systematic quantification of nanoscopic dose enhancement of gold nanoparticles in ion beams.

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Published in 2020 at "Physics in medicine and biology"

DOI: 10.1088/1361-6560/ab7504

Abstract: High-Z material nanoparticles are being studied as localized dose enhancers in radiotherapeutic applications. Here, the nano-scale physical dose en\-hance\-ment of proton, carbon and oxygen ion beam radiation by gold nanoparticles was studied by means of… read more here.

Keywords: ion; systematic quantification; dose enhancement; gold nanoparticles ... See more keywords
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Influence of concentration, nanoparticle size, beam energy, and material on dose enhancement in radiation therapy

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Published in 2017 at "Journal of Radiation Research"

DOI: 10.1093/jrr/rrx009

Abstract: Abstract The purpose of this study was to analyse the effects of the type, concentration, and nanoparticle diameter of dose enhancement materials on the dose enhancement of low- and high-energy megavoltage (MV) X-rays acquired from… read more here.

Keywords: dose enhancement; concentration nanoparticle; energy;
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Nanoparticle dose enhancement of synchrotron radiation in PRESAGE dosimeters.

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Published in 2020 at "Journal of synchrotron radiation"

DOI: 10.1107/s1600577520012849

Abstract: The physical absorbed dose enhancement by the inclusion of gold and bismuth nanoparticles fabricated into water-equivalent PRESAGE dosimeters was investigated. Nanoparticle-loaded water-equivalent PRESAGE dosimeters were irradiated with superficial, synchrotron and megavoltage X-ray beams. The change… read more here.

Keywords: synchrotron; dose enhancement; presage dosimeters; synchrotron radiation ... See more keywords
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Secondary particle production and physical properties during dose enhancement for spread-out Bragg peaks

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Published in 2019 at "Translational Cancer Research"

DOI: 10.21037/tcr.2019.07.54

Abstract: Background The proton therapy is a form of particle radiation therapy that dose enhancement to improve therapeutic ratio (TR) is obtained by high-Z materials. This study evaluated the physical properties of dose enhancement and the… read more here.

Keywords: dose enhancement; secondary particle; production; properties dose ... See more keywords
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Monte Carlo Evaluation of Dose Enhancement Due to CuATSM or GNP Uptake in Hypoxic Environments with External Beam Radiation

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Published in 2020 at "International Journal of Nanomedicine"

DOI: 10.2147/ijn.s241756

Abstract: Purpose Most solid tumors contain areas of chronic hypoxia. Gold nanoparticles (GNP) have been extensively explored as enhancers of external beam radiation; however, GNP have lower cellular uptake in hypoxic conditions than under normoxic conditions.… read more here.

Keywords: hypoxic; cuatsm; external beam; dose enhancement ... See more keywords
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Impact of the Spectral Composition of Kilovoltage X-rays on High-Z Nanoparticle-Assisted Dose Enhancement

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Published in 2021 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms22116030

Abstract: Nanoparticles (NPs) with a high atomic number (Z) are promising radiosensitizers for cancer therapy. However, the dependence of their efficacy on irradiation conditions is still unclear. In the present work, 11 different metal and metal… read more here.

Keywords: composition kilovoltage; def; spectral composition; dose enhancement ... See more keywords
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Secondary Electrons in Gold Nanoparticle Clusters and Their Role in Therapeutic Ratio: The Outcome of a Monte Carlo Simulation Study

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Published in 2022 at "Molecules"

DOI: 10.3390/molecules27165290

Abstract: Gold nanoparticles (GNPs) are used in proton therapy radio-sensitizers to help increase the dose of radiation to targeted tumors by the emission of secondary electrons. Thus, this study aimed to investigate the link between secondary… read more here.

Keywords: monte carlo; role; secondary electrons; gold nanoparticle ... See more keywords