Articles with "dose erlotinib" as a keyword



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Twice weekly pulse and daily continuous‐dose erlotinib as initial treatment for patients with epidermal growth factor receptor–mutant lung cancers and brain metastases

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Published in 2018 at "Cancer"

DOI: 10.1002/cncr.30990

Abstract: In a phase 1 study of pulse/continuous‐dose erlotinib, no patient had disease progression in the central nervous system (CNS). This expansion cohort of the phase 1 study tested the same regimen in a cohort of… read more here.

Keywords: mutant lung; continuous dose; factor receptor; growth factor ... See more keywords
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Pulse-continuous dose erlotinib as initial targeted therapy for patients with EGFR-mutant lung cancers with untreated brain metastases.

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Published in 2017 at "Journal of Clinical Oncology"

DOI: 10.1200/jco.2017.35.15_suppl.9039

Abstract: 9039Background: Clarke (Neurooncol 2010) reported responses with intermittent high pulse doses of erlotinib (leading to higher concentrations in CSF) given to patients with EGFR-mutant central nerv... read more here.

Keywords: egfr mutant; pulse continuous; continuous dose; dose erlotinib ... See more keywords