Does high-dose erythropoietin decrease the risk of death or severe neurodevelopmental impairment in preterm infants?
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Perinatology"
DOI: 10.1038/s41372-021-00931-z
Abstract: Subjects randomized to the intervention arm received highdose EPO (1000 units/kg) intravenous within 24 h of birth and every 48 h for a total of 6 doses, followed by EPO 400 units/kg subcutaneous three times… read more here.
Keywords: decrease risk; death severe; dose erythropoietin; high dose ... See more keywords
Integrating neuroimaging biomarkers into the multicentre, high-dose erythropoietin for asphyxia and encephalopathy (HEAL) trial: rationale, protocol and harmonisation
Sign Up to like & getrecommendations! Published in 2021 at "BMJ Open"
DOI: 10.1136/bmjopen-2020-043852
Abstract: Introduction MRI and MR spectroscopy (MRS) provide early biomarkers of brain injury and treatment response in neonates with hypoxic-ischaemic encephalopathy). Still, there are challenges to incorporating neuroimaging biomarkers into multisite randomised controlled trials. In this… read more here.
Keywords: heal trial; neuroimaging biomarkers; trial; dose erythropoietin ... See more keywords