High-dose hydroxyurea with differentiating agents for treating ultra-high-risk acute promyelocytic leukemia in resource-challenged settings
Sign Up to like & getrecommendations! Published in 2022 at "Acta Oncologica"
DOI: 10.1080/0284186x.2022.2162347
Abstract: Charanpreet Singh, Sarthak Wadhera, Uday Yanamandra, Parathan Karunakaran, Nishant Jindal, Saloni Rani Kumar, Neha Saini, Aditya Jandial, Arihant Jain, Chandan Das, Gaurav Prakash, Alka Khadwal, Shano Naseem , Reena Das, Neelam Varma, Subhash Varma, Pankaj… read more here.
Keywords: agents treating; hydroxyurea differentiating; dose hydroxyurea; high dose ... See more keywords
Randomized Controlled Trial of Fixed Low-Vs Moderate-Dose Hydroxyurea for Primary Stroke Prevention in Sub-Saharan Africa: Final Results of the Spring Trial
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DOI: 10.1182/blood-2020-141436
Abstract: Introduction: In children with sickle cell anemia (SCA) without transcranial Doppler (TCD) screening, the incidence rates of ischemic strokes is approximately the same among children living in low- and high- low-resource settings (Pediatr Neurol. 2019;95:73-78.)… read more here.
Keywords: fixed low; trial; moderate dose; dose hydroxyurea ... See more keywords
Therapeutic Dose of Hydroxyurea-Induced Synaptic Abnormalities on the Mouse Spermatocyte
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2021.666339
Abstract: Hydroxyurea (HU) is a widely used pharmacological therapy for sickle cell disease (SCD). However, replication stress caused by HU has been shown to inhibit premeiotic S-phase DNA, leading to reproductive toxicity in germ cells. In… read more here.
Keywords: therapeutic dose; induced synaptic; dose hydroxyurea; hydroxyurea ... See more keywords