High versus low dose irradiation for tumor immune reprogramming.
Sign Up to like & getrecommendations! Published in 2020 at "Current opinion in biotechnology"
DOI: 10.1016/j.copbio.2020.08.001
Abstract: Local administration of ionizing radiation to tumors can promote anticancer immune responses that lead to the abscopal regression of distant metastases, especially in patients receiving systemic immune-checkpoint inhibitors. Growing preclinical evidence indicates that high-dose irradiation… read more here.
Keywords: irradiation; low dose; immune reprogramming; tumor immune ... See more keywords
The linker of nucleoskeleton and cytoskeleton complex is required for X-ray-induced epithelial-mesenchymal transition
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Radiation Research"
DOI: 10.1093/jrr/rrac104
Abstract: Abstract The linker of nucleoskeleton and cytoskeleton (LINC) complex has been implicated in various functions of the nuclear envelope, including nuclear migration, mechanotransduction and DNA repair. We previously revealed that the LINC complex component Sad1… read more here.
Keywords: sun1; dose irradiation; ray; expression ... See more keywords
Effects of low dose radiation on immune cells subsets and cytokines in mice.
Sign Up to like & getrecommendations! Published in 2020 at "Toxicology research"
DOI: 10.1093/toxres/tfaa017
Abstract: Whole-body exposure to low-dose radiation due to diagnostic imaging procedures, occupational hazards and radiation accidents is a source of concern. In this study, we analyzed the effects of single and long-term low-dose irradiation on the… read more here.
Keywords: irradiation; low dose; long term; dose irradiation ... See more keywords
Effects of Low-dose Splenic Irradiation on T lymphocyte Immune Function
Sign Up to like & getrecommendations! Published in 2022 at "Health Physics"
DOI: 10.1097/hp.0000000000001615
Abstract: Abstract Relevant studies have confirmed that the stimulation of spleen function caused by low-dose splenic irradiation can have positive effects on tumors and other diseases. This study aimed to determine radiation-induced changes in spleen index,… read more here.
Keywords: dose irradiation; group; fractionated irradiation; dose fractionated ... See more keywords
Construction of Radiation Surviving/Resistant Lung Cancer Cell Lines with Equidifferent Gradient Dose Irradiation
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DOI: 10.1177/1559325820982421
Abstract: Radiotherapy plays an increasingly crucial role in the treatment of non-small cell lung cancer (NSCLC). Local tumor recurrence and tumor progression caused by intratumoral heterogeneity induced radiotherapy resistance remain the primary causes of radiotherapy failure.… read more here.
Keywords: surviving resistant; cell lines; dose irradiation; cell ... See more keywords
Superior Antitumor Efficacy of IFN-α2b-Incorporated Photo-Cross-Linked Hydrogels Combined with T Cell Transfer and Low-Dose Irradiation Against Gastric Cancer
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Nanomedicine"
DOI: 10.2147/ijn.s249174
Abstract: Introduction The exhaustion and poor homing of activated lymphocytes are critical obstacles in adoptive cell immunotherapy for solid tumors. In order to effectively deliver immune cells into tumors, we encapsulated interferon-α2b (IFN-α2b) into macroporous hydrogels… read more here.
Keywords: dose irradiation; ifn incorporated; antitumor; low dose ... See more keywords
Alleviation of Severe Skin Insults Following High-Dose Irradiation with Isolated Human Fetal Placental Stromal Cells
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms232113321
Abstract: Skin exposure to high-dose irradiation, as commonly practiced in radiotherapy, affects the different skin layers, causing dry and wet desquamation, hyperkeratosis fibrosis, hard to heal wounds and alopecia and damaged hair follicles. Fetal tissue mesenchymal… read more here.
Keywords: skin; dose irradiation; hair; radiation ... See more keywords