Acute, High Dose Metformin Therapy at Reperfusion Decreases Infarct Size in the High-Risk Aging Heart.
Sign Up to like & getrecommendations! Published in 2023 at "Aging and disease"
DOI: 10.14336/ad.2023.0205
Abstract: Elderly patients (age > 75) sustain larger infarcts with greater mortality from ST elevation myocardial infarcts (STEMI) despite successful reperfusion treatment. Elderly age remains an independent risk despite correction for clinical and angiographic variables. The… read more here.
Keywords: high risk; reperfusion; dose metformin; risk ... See more keywords
Metformin with propofol enhances the scavenging ability of free radicals and inhibits lipid peroxidation in mice.
Sign Up to like & getrecommendations! Published in 2019 at "European review for medical and pharmacological sciences"
DOI: 10.26355/eurrev_201906_18089
Abstract: OBJECTIVE The aim of this study was to investigate the effects of metformin on anesthetic effect and anti-oxidative capacity in mice anesthetized with propofol. MATERIALS AND METHODS A total of 150 C57BL/6 mice were randomly… read more here.
Keywords: metformin propofol; scavenging ability; mice; dose metformin ... See more keywords
A Metabolic Pattern in Healthy Subjects Given a Single Dose of Metformin: A Metabolomics Approach
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2021.705932
Abstract: Metformin is a widely prescribed medication for the treatment of type 2 diabetes mellitus (T2DM). It possesses effective roles in various disorders, including cancer, dyslipidemia, and obesity. However, the underlying mechanisms of metformin's multiple benefits… read more here.
Keywords: metformin; dose metformin; healthy subjects; single dose ... See more keywords
Factors Determining Blood and Urine Concentrations of Metformin among Patients with Type 2 Diabetes: A Cross Sectional Study
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Biomedical Science"
DOI: 10.4172/2254-609x.100093
Abstract: Background: Diabetes Mellitus (DM) is a chronic medical condition characterized by high levels of blood glucose due to a dysfunction in the amount or the function of the hormone insulin. Among the oral hypoglycaemic drugs… read more here.
Keywords: cross sectional; sectional study; blood urine; dose metformin ... See more keywords